#United States #Brea, California #Gut Health #NuLiv Science #AstraGin

NuLiv Science Unveils AstraGin®'s Health Benefits

NuLiv Science, a pioneer in the field of plant-based nutraceutical ingredients, has recently made headlines with its latest study on AstraGin®, a patented compound derived from Astragalus membranaceus and Panax notoginseng. This cutting-edge research focuses on AstraGin®'s remarkable ability to support intestinal barrier integrity and enhance the adhesion of probiotics, thus playing a vital role in gut health, particularly during inflammatory conditions.

Study Overview

Published in the esteemed journal Bioactive Compounds in Health and Disease, this preclinical study aimed to evaluate the effects of AstraGin® on maintaining intestinal health. The researchers utilized a widely accepted in-vitro model using human Caco-2 cells to simulate intestinal epithelial barrier function under inflammatory stress induced by lipopolysaccharide (LPS).

Key Findings

The results of the study were compelling. AstraGin® was shown to significantly improve several indicators of intestinal barrier health, including:
1. Increased Transepithelial Electrical Resistance (TEER): A critical measure indicating enhanced barrier function.
2. Reduced FITC-Dextran Permeability: Lower permeability is associated with a healthier gut barrier, preventing unwanted substances from translocating across the epithelium.
3. Restoration of Key Tight Junction Proteins: AstraGin® positively impacted the expression of important proteins such as Claudin-1, Occludin, and ZO-1, essential for tight junctions that maintain barrier integrity.
4. Recovery of Cellular ATP Levels: This is significant as ATP serves as a primary energy source for cellular functions, suggesting improved cell vitality.

Additionally, AstraGin® significantly promoted the growth and adhesion of Lactobacillus rhamnosus, a beneficial probiotic, enhancing its interaction with intestinal cells even in inflammatory conditions. This preserves and encourages a healthy microbiota composition crucial for digestive wellness.

Implications for Gut Health Products

Richard Wang, CEO of NuLiv Science, emphasized the importance of these findings. He stated, “This study reinforces our earlier human research showing increases in beneficial gut bacteria with AstraGin®. The data adds another dimension for brands formulating gut health products to really deliver for their end users.” This statement underscores AstraGin®’s potential role as a functional ingredient for various dietary supplements and gut health products, offering a scientifically-backed approach for formulation.

Conclusion

In conclusion, the study highlights AstraGin® as not just an ingredient but a significant advancement in maintaining a healthy gastrointestinal environment. The protective effects observed during LPS-induced inflammation further enhance its appeal as a vital component in nutritional formulations aimed at promoting gut health.

For brands looking to innovate in gut health solutions, AstraGin® may offer the research-backed advantages necessary to effectively support consumer health in an ever-demanding market.

For more detailed information about AstraGin® and to explore the extensive array of preclinical and human studies underpinning its efficacy, visit NuLiv Science's website. NuLiv Science’s commitment to research-driven products aligns with its vision of empowering individuals to achieve healthier lives by leveraging the wisdom of Traditional Chinese Medicine (TCM) through advanced scientific methods.