SciBase's New Research Unveils Nevisense's Capabilities in Aging Skin Detection

SciBase Reveals Groundbreaking Research on Nevisense in Aging Skin Detection

In a significant advancement for dermatology, SciBase Holding AB, a pioneer in AI-driven diagnostic solutions for skin disorders, has announced a compelling new study at the 2026 Society for Investigative Dermatology (SID) Annual Meeting. The research, helmed by renowned professors Abuabara and Dr. Zhu from the University of California, San Francisco (UCSF), explores the efficacy of SciBase's Electrical Impedance Spectroscopy (EIS) technology as employed in its Nevisense platform. This study aims to highlight the capability of Nevisense in detecting and quantifying changes in the skin barrier due to aging.

Expanding Nevisense's Potential

Nevisense is already a tried-and-tested technology for identifying melanoma and assessing skin barriers in conditions such as atopic dermatitis. With this fresh research, its applications now extend into the realm of geriatric dermatology, making it a valuable tool for longevity science. As our understanding of skin health evolves, research like this is essential in developing targeted therapies based on age-related skin challenges.

Key Findings from the Research Study

The cross-sectional study detailed in this announcement compared EIS measurements between two distinct age groups: young adults with a mean age of 25.9 and older adults averaging 79.1 years. By harnessing a comprehensive analysis of the 700 parameters collected via each Nevisense measurement, the researchers devised a 'composite barrier score' that serves as a significant determinant in understanding skin health across ages.

1. Precision Detection: One of the standout outcomes was the identification of 35 specific age-associated EIS features on the skin, particularly on the forearm, showcasing the technology's precision in revealing skin barrier dynamics.

2. Strong Correlation: The research found a robust correlation between the composite barrier score and age, with a Spearman correlation coefficient of 0.69. This reinforces the EIS capability to identify subtle alterations in skin structure and composition as humans age, crucial for dermatologists seeking to tailor personalized skin care regimens.

3. Advanced Analytics: The research posits that analyzing specific EIS features offers a markedly more sensitive evaluation of age-related skin barrier changes compared to traditional assessment methods, which rely on summarized values alone.

Insights from Leadership

Pia Renaudin, CEO of SciBase, expressed her enthusiasm for the findings, stating, "These results are a remarkable evolution for SciBase. It's vital to comprehend how skin barriers transform with age, not just for clinical dermatology but also for creating effective skin care practices. This research validates that our EIS technology extends beyond skin cancer diagnostics; it is a versatile platform for intricate, non-invasive skin evaluations."

The abstract of this pivotal study is titled "Electrical Impedance Spectroscopy Detects Age-Related Skin Barrier Changes," which can be referenced in abstract booklet SID_Chicago26_Abstract_Final_web.pdf. The concluding remarks highlight the promising potential of EIS technology in recognizing age-related skin barrier changes in vivo.

Next Steps for Validation

Looking ahead, SciBase is keen to validate these findings through additional studies that will refine the composite barrier score for real-world clinical applications and further research. This is an exciting time for both the company and the dermatological community, as the advances in technology can lead to new strategies for enhancing skin health as we age.

For more information, interested parties can reach out to Pia Renaudin, CEO at SciBase, via phone at +46 73 206 98 02 or email [email protected]. SciBase, listed on the Nasdaq First North Growth Market since June 2, 2015, continues its commitment to developing innovative solutions aimed at improving patient care and reducing healthcare costs worldwide.

To learn more about SciBase, visit www.scibase.com for press releases and financial reports.