TC BioPharm Announces Changes in ADS Ratio to Enhance Shareholder Value

In a significant development, TC BioPharm (Holdings) PLC, the clinical-stage biotechnology company known for its groundbreaking allogeneic gamma-delta T cell therapies, is set to adjust the ratio of its American Depositary Shares (ADSs) to ordinary shares. This change will transition from the current structure of one ADS representing two hundred ordinary shares to a new structure where one ADS will represent four thousand ordinary shares. This strategic decision, effective February 10, 2025, aims to optimize shareholder engagement and enhance trading levels for the company's shares on the Nasdaq Capital Market, where they are listed under the ticker symbol 'TCBP'.

The upcoming ADS ratio alteration closely resembles a 1-for-20 reverse stock split, simplifying the share structure without affecting the total number of underlying ordinary shares. In practical terms, for every twenty ADSs held, shareholders will receive one new ADS. This will assure the continuity of trade on Nasdaq while also aggregating fractional shares due to the ratio change, which will be converted into cash distributions for shareholders holding fractions.

Moreover, TC BioPharm emphasizes that this move is not merely procedural but reflects the company’s promise of improved trading conditions and shareholder value, although they caution that future trading prices may not precisely reflect previous patterns. This is a crucial tactic, as the biopharmaceutical firm seeks to position itself favorably amidst an intensely competitive biotechnology market.

Stepping back from the immediate changes, it is essential to underscore TC BioPharm's wider ambition. The firm is primarily centered on innovating gamma-delta T cell therapies, which utilize naturally occurring immune cells known for their unique ability to distinguish healthy tissues from diseased ones. The company's innovation has progressed to human efficacy data specifically for acute myeloid leukemia treatment, showcasing its leadership within the biopharmaceutical realm.

Currently, TC BioPharm is at the forefront of developing these therapies, conducting pivotal phase II clinical trials to validate the safety and efficacy of its unmodified gamma-delta T cell product. The company is also advancing with its proprietary allogeneic CryoTC technology, allowing cold storage of product, thus providing time-efficient operations for clinics worldwide.

This forward-looking strategy is not without its challenges. The company acknowledges potential risks associated with the biotechnology field, including unfavorably variances in actual outcomes compared to projections. However, TC BioPharm remains committed to extending its reach and enhancing patient outcomes through innovative treatment methodologies.

In conclusion, the ADS ratio change at TC BioPharm is a deliberate step towards strengthening the company's market presence while continuing to innovate within the healthcare sector. Investors will keenly observe how this structural adjustment influences trading dynamics and overall market response as TC BioPharm embarks on its journey to revolutionize cancer treatment with gamma-delta T cell therapies.

About TC BioPharm


TC BioPharm is a leading clinical-stage biopharmaceutical company dedicated to developing and commercializing groundbreaking gamma-delta T-cell therapies for various cancer treatments. Committed to enhancing human health by leveraging the body’s own immune capabilities, TC BioPharm is setting a new standard in the oncology space. With ongoing clinical trials and a commitment to patient safety and efficacy, TC BioPharm is paving the way for next-generation cancer therapies.

Topics Health)

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