Integration of Advanced Cellular Imaging System by Araceli Biosciences and Ginkgo Bioworks
In a groundbreaking development for the biotechnology field, Araceli Biosciences and Ginkgo Bioworks recently announced the integration of Araceli's Endeavor® high-content imaging instrument into Ginkgo's Nebula autonomous laboratory located in Boston. This state-of-the-art imaging system, recognized as the fastest in the world, is designed to augment the existing technologies at Nebula. By providing real-time cellular imaging alongside comprehensive data analysis, this integration gives researchers access to a wealth of validated datasets crucial for training and validating AI models geared towards drug discovery.
The Nebula laboratory utilizes Ginkgo's Reconfigurable Automation Carts (RAC). Each RAC is a modular unit equipped with robotic arms, an automated sample transport system, and unified control software, allowing scientists to adapt and reconfigure instruments as workflows evolve. With over 100 RACs operational in Nebula, researchers can conduct significant scientific studies that produce data within a fast turnaround time; typically, protocols submitted by scientists yield results by the following day. This setup enables the Nebula lab to execute the work of multiple scientists concurrently and autonomously. Notably, Nebula occupies only about one-third of the physical space that a conventional laboratory would require for similar tasks.
One of the standout features of the Endeavor system is its ability to scan a 1,536-well plate in under four minutes, functioning seamlessly within the RAC's framework and operating continuously alongside ongoing experiments. With the integration of Araceli's ClaireRT™ software, the Endeavor is not just a passive data collector. Instead, it actively analyzes each well during image capture; if any well does not meet predefined criteria, the system can alert operators or halt image acquisition, thereby addressing issues before proceeding with experiments.
According to Matt Beaudet, President and CEO of Araceli Biosciences, "The next generation of AI for drug discovery requires a radically different volume of biological data. The lab itself is evolving; it now generates cellular data, interprets its findings, and reacts in real-time. This capability is enabled through the collaboration with Ginkgo and the high-resolution imaging analytics at scale brought into the mix."
Jason Kelly, Co-Founder and CEO of Ginkgo Bioworks, emphasized the significance of incorporating cutting-edge equipment into autonomous laboratories: "Each addition of advanced instruments, like the Endeavor imaging technology, enhances the value of your autonomous lab. With Nebula, every researcher can seamlessly access this high-content imaging technology and integrate it with existing tools."
Araceli Biosciences is committed to developing the fastest high-content imaging instruments and AI-based analysis software for AI-driven automated labs. The integrated solutions they provide offer real-time cellular insights enabling automated workflows to manage quality and facilitate decision-making at every stage of an experiment. This advancement supports biotech and pharmaceutical companies as they accelerate their discoveries and execute them with increased confidence.
Meanwhile, Ginkgo Bioworks is focused on advancing tools that simplify biological engineering for a wider audience. Their autonomous laboratories aim to replace manual tasks with robotic systems, significantly boosting researchers' productivity. Moreover, Ginkgo is also making their internal autonomous laboratory accessible as a 'cloud laboratory' through their Datapoints and Contract Research Solutions services.
In essence, this merger of technology marks a crucial step toward making experimental science more scalable and accessible across various sectors, including food, agriculture, pharmaceuticals, and specialty chemicals. Furthermore, Ginkgo Bioworks leads the way as a comprehensive horizontal platform for cellular programming, facilitating flexible and integrated services for businesses tackling their unique challenges.
In summary, the collaboration between Araceli Biosciences and Ginkgo Bioworks sets the stage for transformative advancements in drug discovery processes, with their integration of advanced imaging technologies allowing for better data and more efficient workflows, ultimately revolutionizing the field of biotechnology.
The Nebula laboratory utilizes Ginkgo's Reconfigurable Automation Carts (RAC). Each RAC is a modular unit equipped with robotic arms, an automated sample transport system, and unified control software, allowing scientists to adapt and reconfigure instruments as workflows evolve. With over 100 RACs operational in Nebula, researchers can conduct significant scientific studies that produce data within a fast turnaround time; typically, protocols submitted by scientists yield results by the following day. This setup enables the Nebula lab to execute the work of multiple scientists concurrently and autonomously. Notably, Nebula occupies only about one-third of the physical space that a conventional laboratory would require for similar tasks.
One of the standout features of the Endeavor system is its ability to scan a 1,536-well plate in under four minutes, functioning seamlessly within the RAC's framework and operating continuously alongside ongoing experiments. With the integration of Araceli's ClaireRT™ software, the Endeavor is not just a passive data collector. Instead, it actively analyzes each well during image capture; if any well does not meet predefined criteria, the system can alert operators or halt image acquisition, thereby addressing issues before proceeding with experiments.
According to Matt Beaudet, President and CEO of Araceli Biosciences, "The next generation of AI for drug discovery requires a radically different volume of biological data. The lab itself is evolving; it now generates cellular data, interprets its findings, and reacts in real-time. This capability is enabled through the collaboration with Ginkgo and the high-resolution imaging analytics at scale brought into the mix."
Jason Kelly, Co-Founder and CEO of Ginkgo Bioworks, emphasized the significance of incorporating cutting-edge equipment into autonomous laboratories: "Each addition of advanced instruments, like the Endeavor imaging technology, enhances the value of your autonomous lab. With Nebula, every researcher can seamlessly access this high-content imaging technology and integrate it with existing tools."
Araceli Biosciences is committed to developing the fastest high-content imaging instruments and AI-based analysis software for AI-driven automated labs. The integrated solutions they provide offer real-time cellular insights enabling automated workflows to manage quality and facilitate decision-making at every stage of an experiment. This advancement supports biotech and pharmaceutical companies as they accelerate their discoveries and execute them with increased confidence.
Meanwhile, Ginkgo Bioworks is focused on advancing tools that simplify biological engineering for a wider audience. Their autonomous laboratories aim to replace manual tasks with robotic systems, significantly boosting researchers' productivity. Moreover, Ginkgo is also making their internal autonomous laboratory accessible as a 'cloud laboratory' through their Datapoints and Contract Research Solutions services.
In essence, this merger of technology marks a crucial step toward making experimental science more scalable and accessible across various sectors, including food, agriculture, pharmaceuticals, and specialty chemicals. Furthermore, Ginkgo Bioworks leads the way as a comprehensive horizontal platform for cellular programming, facilitating flexible and integrated services for businesses tackling their unique challenges.
In summary, the collaboration between Araceli Biosciences and Ginkgo Bioworks sets the stage for transformative advancements in drug discovery processes, with their integration of advanced imaging technologies allowing for better data and more efficient workflows, ultimately revolutionizing the field of biotechnology.
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