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CeraVe and L'Oréal Groupe Triumph with IFSCC Research Award

In an impressive display of scientific achievement, CeraVe and L'Oréal Groupe announced that their joint research on scalp biology has been awarded the prestigious Applied Research Award at the 35th International Federation of Societies of Cosmetic Chemists (IFSCC) Congress. This accolade signifies a pivotal advancement in understanding dandruff and the underlying science of the scalp barrier.

Gene Colón, Global Senior Vice President of Medical Affairs and Communications at CeraVe, expressed pride in the recognition, emphasizing the collaborative effort toward scientific innovation and a deeper understanding of the skin and scalp barrier's complex biology. He stated, "This groundbreaking research extends beyond traditional dandruff perspectives, spotlighting the role of ceramide deficiency and scalp barrier dysfunction, critical bacterial components, and the influence of ethnicity. To a large extent, it significantly enhances our scientific comprehension based on our core ceramide science, offering new avenues for future innovations."

The awarded study, heralded as the first of its kind, involved a meticulous comparison between dandruff-affected and healthy scalps, exploring clinical symptoms, ceramide profiles, microbiome composition, and inflammatory markers. This comprehensive approach aims to provide the most extensive view of dandruff pathophysiology to date. Researchers from L'Oréal surveyed over 200 participants from diverse racial and ethnic backgrounds, which added to the study's robustness.

Qian Zheng, Ph.D., Senior Vice President of Advanced Research for North America and Global Head for Regenerative Beauty at L'Oréal Groupe, noted, "This award reflects the leadership of L'Oréal’s research and innovation teams in scientific advancement and underscores our mission to keep pioneering skin, hair, and scalp research. By integrating microbiome research with barrier biology through an inclusive lens, our teams are at the forefront of developing new scalp care approaches, translating biological insights into targeted, effective solutions for consumers globally."

The new and unpublished findings build upon previous microbiome research published in the Journal of Drugs in Dermatology, expanding its scope significantly. While prior studies characterized the scalp microbiome in a global population, the IFSCC-recognized research delves deeper, examining ethnic differences and exploring the functional profile of the microbiome for the first time. This comprehensive analysis, along with insights on microbial targets beyond Malassezia – a fungus traditionally associated with dandruff – represents a major breakthrough in understanding dandruff biology.

Key discoveries from the study include:

• - Bacterial Drivers: Staphylococcus aureus (S. aureus) and Staphylococcus capitis (S. capitis), common skin bacteria, were significantly more prevalent in dandruff across all ethnicities.
• - S. aureus Correlation: A remarkable positive correlation was established between the frequency of S. aureus and the presence and severity of dandruff.
• - Virulence Factors: Dandruff-scalp harbored notably higher concentrations of virulence factor (VF) genes, particularly among Latino/Hispanic and Asian groups, many of which have been linked to the pathogenicity of S. aureus.
• - Personalized Treatments: This study is the first to characterize how scalp microbiomes function differently in dandruff across diverse ethnicities, emphasizing the need for tailored treatment approaches.
• - Ethnic Disparities: Malassezia was more prevalent in all ethnic groups except for Asian Americans, and Malassezia globosa, frequently linked to scalp health, was prevalent in healthy scalps across all populations.

The annual IFSCC Congress is a highly esteemed international event in cosmetic science, uniting leading figures to showcase the latest scientific advancements in the industry.

About CeraVe

Founded in 2005, CeraVe was established with the goal of providing therapeutic skincare for everyone. The brand develops products in collaboration with dermatologists to restore and maintain the skin's natural barrier. Each CeraVe formula is enriched with three essential ceramides (Ceramide 1, 3, and 6-II) and selected products feature MVE Technology for controlled, sustained hydration. CeraVe is the number one dermatological skincare brand in the USA and is recommended by over 90,000 dermatologists worldwide. The brand is now available in over 100 countries. For more information, visit the brand on social media or www.cerave.com.

About L'Oréal

For 115 years, L'Oréal has dedicated itself to fulfilling the beauty aspirations of consumers worldwide. Their mission is to create beauty that moves the world, defining their approach to beauty as essential, inclusive, ethical, generous, and committed to social and ecological sustainability. With a portfolio of 37 international brands and ambitious sustainability goals, L'Oréal aims to offer the best in quality, efficacy, safety, integrity, and responsibility while celebrating beauty in its infinite diversity. In 2024, the group reported sales of 43.48 billion euros, supported by a robust global workforce of over 90,000 employees and a balanced geographical presence. L'Oréal is a recognized innovator, recently winning accolades for being the most innovative company in Europe. For more details, visit https://www.loreal.com/en/mediaroom.