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Nira Medical and Rocky Mountain MS Clinic Launch Groundbreaking AI Registry for MS

Nira Medical, in collaboration with the Rocky Mountain Multiple Sclerosis Clinic (RMMSC), recently unveiled a pioneering artificial intelligence (AI)-powered registry aimed at enhancing research and treatment protocols for multiple sclerosis (MS). This significant announcement took place at the 2025 European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Congress, which is being held from September 24 to 26.

Transforming MS Research with AI

the joint research poster presented, titled "A Novel Large Language Model Approach for Building a Real-World Multiple Sclerosis Disease Registry," underscores the potential of using extensively developed AI technologies to convert disparate electronic health record (EHR) data into a unified, scalable MS registry. Current MS registries predominantly rely on time-consuming manual chart reviews that limit their efficacy and scope, impacting the understanding of treatment outcomes across diverse patient populations.

To address these limitations, the collaboration introduces the Century Health Abstraction and Retrieval Model (CHARM), a large language model specifically calibrated to interpret MS-related clinical data. This AI approach successfully processed data from over 4,200 RMMSC patients, effectively extracting detailed clinical variables like the Expanded Disability Status Scale (EDSS) scores, timelines for disease-modifying therapies, MRI findings, and instances of relapses.

Key Findings and Implications

The team's findings reveal a shift in the efficiency of data abstraction processes. Notably, the implementation of CHARM led to accurate abstraction of EDSS data in over 97% of patient visits. Among the participants, a staggering 79.5% experienced at least one relapse, with 84% receiving B-cell therapy. These insights not only cement the significance of robust data collection but also illustrate the potential for more comprehensive understandings of MS subtypes, treatment histories, and imaging patterns.

Dr. John Foley, a neurologist with the RMMSC, expressed the importance of unlocking EHR data for enhancing real-world evidence in neurology. He stated, "By structuring raw data at scale, we're laying the groundwork for a more complete and representative understanding of MS." This perspective highlights the crucial role data plays in refining therapies and supporting clinical decision-making efforts.

Additionally, Rebekah Foster, Head of Data at Nira Medical, noted the empowerment that AI brings to MS research by overcoming traditional data barriers. The novel methodology not only accelerates research capacity but also fine-tunes the accuracy of clinical insights, thereby facilitating better patient care outcomes across varying demographics.

The Future of MS Registries

With the potential to enhance clinical trials and drug development timelines significantly, this AI-powered methodology allows researchers to overcome traditional time constraints associated with data collection. It transforms what would take months of manual work into a swift and streamlined process, allowing for larger and more representative MS registries to emerge.

Nira Medical stands as the nation's largest independent neurology platform, aiming to revolutionize patient care through an emphasis on advanced neurological conditions. Partnering with recognized leaders like the Rocky Mountain MS Clinic, Nira Medical hopes to expand access to high-quality care, particularly across underserved regions.

As for the RMMSC, it has earned national acclaim for its continuous commitment to innovating MS treatment and management, driven by over 35 years of experience. Together with Century Health, these collaborations unfold a future where AI not only facilitates efficient data processing but also enriches the overall quality of healthcare services for MS patients.

For more information on this innovative approach to MS treatment and research, visit www.century.health.