#Canada #Toronto #Drug Development #Xtalks #in vivo models

Unlocking Preclinical Success with Advanced In Vivo Efficacy Models

In the evolving landscape of pharmaceutical research, the role of in vivo efficacy models has never been more critical. Aiming to bridge the gap between laboratory tests and clinical trials, these models are essential for assessing drug behaviors, efficacy, and safety. As such, Xtalks is hosting a complimentary webinar that dives deep into these advanced pharmacokinetic/pharmacodynamic (PK/PD) models and their importance in fueling success in oncology, immunology, and fibrosis research.

Scheduled for Tuesday, August 26, 2025, at 11 AM EDT, this interactive session will feature industry experts from Aragen Bioscience, including Dr. Malavika Ghosh, Sr. VP and Head of Global Preclinical Research Services, and Dr. Linh Nguyen, Director of Oncology Immunology. They will guide participants through real-world case studies that highlight the application and benefits of in vivo efficacy models, illustrating how they can effectively support decision-making processes and expedite program timelines.

In this dynamic session, attendees can expect insights into discovering emerging trends in in vivo modeling, including the use of state-of-the-art translational toolkits such as patient-derived xenograft (PDX) and humanized models. These advanced platforms emphasize the increasing demand for predictive, scalable preclinical models within the pharmaceutical landscape. Participants will learn how validated and customized in vivo systems efficiently create disease-relevant models that closely mirror human pathophysiology, confirming mechanisms of action through integrated PK/PD studies and biomarker analyses.

Moreover, the discussion will shed light on the careful design of study frameworks tailored to clinical and regulatory goals, ensuring that the research aligns with required standards. Complemented by advanced analytics techniques, such as digital histopathology, these innovative approaches will offer quantifiable insights that enhance the preclinical development process.

This webinar serves not only as a platform for knowledge exchange but also as an opportunity for researchers and industry practitioners to embrace a collaborative, science-driven approach. Understanding how to implement these models can drastically improve predictive accuracy and streamline the path to IND-enabling milestones.

For those interested in achieving substantial advancements in drug development, registering for the Xtalks webinar is invaluable. By joining industry leaders, participants will gain practical strategies and expertise that can facilitate the efficient transition from laboratory discoveries to clinical applications.

To register for this insightful event, visit the registration link for the webinar on Advanced In Vivo Efficacy Models for Preclinical Success. Don't miss the chance to transform your drug development strategies with the latest insights and innovative solutions in the industry.