SamaCare, an innovative cloud-based platform focused on patient access for specialty medications, has made a remarkable leap in its growth journey by being ranked No. 578 on the prestigious Inc. 5000 list for 2025. This annual list showcases America's fastest-growing private companies, making it a significant achievement for any business. This marks SamaCare's second appearance on the list, reinforcing its position in the healthcare technology arena among some of the most influential entities.
Founded by Syam Palakurthy, SamaCare aims at improving patient access to vital therapies, thus removing administrative hurdles that often obstruct timely treatment. With a commitment that is rooted in empathy and human impact, Palakurthy states, "SamaCare's growth is directly tied to real human impact—that's what truly motivates us." By providing a seamless experience in the prior authorization process, SamaCare’s platform has influenced the healthcare landscape positively, enabling patients to start potentially life-saving therapies without unnecessary barriers.
On the Inc. 5000 list, SamaCare achieved an impressive No. 68 ranking among healthcare and medical services companies and was positioned No. 94 within California's thriving business ecosystem. Executive Bradley Sloan from Questa Capital praised the company, "It's remarkable to see SamaCare reach the #94 spot in California's Inc. 5000 rankings—a state that's home to some of the world's most innovative and well-funded private companies." He furthermore emphasized that SamaCare’s advancements not only benefit itself but also contribute valuable improvements to the healthcare system at large.
SamaCare utilizes a unique Script-to-Therapy Operating System™ that significantly enhances the prior authorization, enrollment, and verification processes for medical practices. By amalgamating AI technology with expert human intervention, the platform resolves over one million prior authorizations across a vast network that includes more than 20,000 providers and clinics. This capability is not merely about processing requests more efficiently; it also involves generating insightful data regarding obstacles that patients face when trying to access their prescribed therapies. Such insights allow pharmaceutical market access teams to actively target interventions and enhance patient and clinician education.
The sheer volume of funding allocated by pharmaceutical companies for developing and marketing new treatments demonstrates the necessity of closing existing gaps in treatment access. By arming stakeholders with insights that shed light on patient experiences and hurdles, SamaCare is assisting in refining the healthcare ecosystem. As Mike Hofman, editor-in-chief of Inc., notes, "Making the Inc. 5000 is always a remarkable achievement, but earning a spot this year speaks volumes about a company's tenacity and clarity of vision," highlighting that such companies flourish even in challenging times.
The methodology behind the Inc. 5000 list involves a rigorous assessment of percentage revenue growth from the years 2021 to 2024. To qualify, companies must be privately held, for-profit, U.S.-based, and not simply extensions of larger conglomerates. Furthermore, they must have achieved a minimum revenue of $100,000 in 2021 and $2 million by 2024.
SamaCare continues to evolve and is currently engaged with multiple specialties, including retina, oncology, neurology, and rheumatology practices, which collectively account for more than $20 billion in annual specialty drug spending. The swift growth of SamaCare underscores not just a business success story but a commitment to improving access to life-altering therapies for patients across the nation. As the company forges ahead, it remains dedicated to its mission of delivering essential solutions that pave the way for enhanced patient care and improved lives.
For more details and insights on SamaCare’s offerings and future plans, visit
SamaCare’s official website.