#South Korea #Seoul #Amorepacific #BluePDRN #Skin Regeneration

Amorepacific’s Groundbreaking Research on Microalgal-Derived PDRNs

In an exciting development for skincare innovation, Amorepacific has unveiled research that highlights the skin-enhancing properties of polydeoxyribonucleotides (PDRNs) sourced from a unique microalgal species, Chlorella protothecoides. These findings, published in the respected journal Archives of Dermatological Research, detail the mechanisms through which these microalgal-derived PDRNs, branded as BluePDRN™, demonstrate remarkable efficacy in promoting skin regeneration and healing wounds.

The Shift Towards Sustainable Solutions

Traditionally, PDRNs have been acquired from animal sources, predominantly salmon and trout. However, recognizing the need for sustainable and ethical beauty alternatives, Amorepacific's research team has shifted focus to microalgae. This innovative approach not only alleviates concerns about animal ethics but also presents a scalable solution that can meet growing global demands for cruelty-free skincare products.

Key Findings from the Research

Amorepacific's research, conducted at their renowned RI Center, was part of a larger initiative backed by South Korea's Ministry of Oceans and Fisheries. The study revealed that BluePDRN™ could achieve skin regeneration efficacy comparable to that of PDRNs sourced from salmon. Notably, BluePDRN™ boasts a significantly smaller molecular size—approximately 1/20th that of traditional PDRN—making it easier for skin to absorb and utilize its regenerative properties.

In vitro experiments demonstrated that BluePDRN™ effectively promoted wound healing by enhancing collagen accumulation and encouraging angiogenesis, essential processes for maintaining healthy skin. Importantly, these effects were achieved through mechanisms that depend on the adenosine A2A receptor (A2AR), a crucial pathway in skin regeneration.

Extensive Impact on Skin Health

The benefits of BluePDRN™ were further validated through experiments conducted in collaboration with Outer Biosciences Inc., a biotechnology firm based in Boston. Their tests showed impressive results, particularly in skin tissues suffering from damage due to photoaging, a common concern faced by individuals in diverse demographics. By rejuvenating the skin’s natural barrier and encouraging healing from within, BluePDRN™ stands to be a game-changer in the skincare landscape.

Future Potential and Commitment to Innovation

CTO of Amorepacific RI Center, Byung-Fhy Suh, emphasized the significance of these findings, stating, “This research underlines the potential of sustainable, vegan PDRNs derived from microalgae. Our goal is to deliver safer and more effective skincare solutions to consumers globally.”

To protect their novel formulation, Amorepacific has applied for a patent for the technology that allows for the continuous and efficient production of low-molecular-weight PDRN from microalgae. Additionally, their commitment to this groundbreaking innovation has been recognized with a New Excellent Technology (NET) certification and a commendation from the Ministry of Oceans and Fisheries.

Conclusion

The introduction of BluePDRN™ is not just a leap forward for Amorepacific, but for the entire skincare industry, illustrating how advancements in biotechnology and ecological responsibility can go hand in hand. Consumers are increasingly seeking products that align with their values, and this innovative PDRN offers a proactive step towards ethical and effective skincare solutions. As Amorepacific continues to explore the applications of microalgae in beauty, the future of skincare looks effectively promising.