#USA #Boston #Volta Labs #Twist Bioscience #Callisto Platform

Volta Labs Launches Automated Hybridization Capture Solution

In a significant advancement for the field of genomic research, Volta Labs has officially introduced its Hybridization Capture App compatible with the Twist Standard Hybridization v2 Kit, integrated within its Callisto platform. This groundbreaking development promises to streamline workflows for researchers and clinical laboratories by enhancing the accuracy and consistency of genomic sampling processes.

The new hybridization capture process, developed in collaboration with Twist Bioscience, leverages the industry-leading hybrid capture chemistry of Twist, combined with Volta’s fully automated Callisto platform. This cutting-edge integration not only simplifies complex workflows but also ensures a remarkably consistent enrichment performance that researchers can rely on.

Benefits of Automation in Genetic Research

Udayan Umapathi, CEO of Volta Labs, highlights the significance of this collaboration: "By blending Twist’s proven v2 kit with Callisto’s unique architecture, which is designed for precise temperature-controlled automation, we’ve refined the hybrid capture workflow. This results in a uniformly consistent enrichment within a solution that is simple, reliable, and user-friendly for every laboratory."

Hybrid capture is crucial for targeted sequencing applications, especially when dealing with large panels or when identifying new variants is essential. Historically, these workflows have been labor-intensive, often requiring specialized technical skills. The Callisto platform automates these critical steps, reducing manual interventions that can lead to error and inconsistencies.

Precision and Consistency with Callisto

The distinctive architecture of Callisto enables precise manipulation of magnetic beads along with uninterrupted and consistent temperature control throughout the hybrid capture process. This design directly contributes to maintaining consistent enrichment performance while eliminating the variability common to manual or semi-automated techniques. By using Callisto, laboratories can perform the hybrid capture portion of their workflow with ease, reliability, and full automation.

A key advantage of this solution is the reduced need for repeat runs, which not only decreases operational costs but also enhances the overall efficiency of sequencing tasks. The platform provides laboratories with the assurance of uniform coverage across a broad range of panels, which is essential in genomic assessments.

Advantages of Twist Standard Hybridization v2 Kit

The Twist Standard Hybridization v2 Kit stands out due to its silicon platform and capability for high-scale DNA synthesis, allowing Twist to develop NGS tools with remarkable uniformity. This kit offers researchers consistent coverage and high sensitivity across their targeted regions, further solidifying the quality of research outputs.

Emily M. Leproust, CEO and co-founder of Twist Bioscience, emphasizes the benefits of this innovative collaboration: "We’ve designed our Twist NGS tools to empower customers in accelerating their research while lowering the costs associated with downstream sequencing. By integrating our Twist Standard Hybridization v2 Kit with Callisto’s automated platform, we are optimizing workflows for our clients, ensuring exceptional performance and efficiency."

Conclusion

The launch of the Hybridization Capture App on the Callisto platform represents a transformative moment for genomic research, where streamlined processes and enhanced reliability are now within reach for laboratories worldwide. With tools designed to elevate research efficiency, Volta Labs continues to push the boundaries of innovation in genomic science. For more details, visit Volta Labs’ website or the specific page for the Twist Hybrid Capture App.

For further inquiries, media contacts are available at:
Nicole Ellis Ovadia
Director of Strategic Marketing
Email: [email protected]

Website: Volta Labs

This unique blend of technology and innovation heralds a new era for researchers dedicated to unraveling the complexities of genomics, promising greater accuracy and efficiency in their essential work.