#Israel #Neuromodulation #Herzliya #Corundum Neuroscience #Tel Aviv University

Corundum Neuroscience Awards Research Grant

Corundum Neuroscience, a prominent venture builder in the field of neuroscience, has made headlines with its recent research grant awarded to a team at Tel Aviv University. This funding, aimed at enhancing our understanding of the brain's roles in immune regulation, promises to shed light on potential therapeutic avenues for autoimmune and inflammatory diseases.

The principal investigator, Professor Asya Rolls from the Department of Neuroscience, will spearhead a project that ambitiously seeks to map specific brain regions implicated in immune responses. By utilizing advanced viral tracing techniques, the study aims to identify areas of the brain that become activated during various inflammatory states. This approach has the potential to revolutionize how medical professionals understand and treat conditions such as Crohn's disease, multiple sclerosis, and type 1 diabetes.

A key aspect of this research will involve creating detailed maps of the brain areas engaged during immune responses. The team will utilize models of colon and skin inflammation, observing how these immune responses correlate with brain activity. By ultimately correlating animal model data with insights from large longitudinal human studies, researchers hope to pinpoint key intervention targets. Several autoimmune disorders exhibit a neuro-immunological connection, and understanding these pathways could redefine treatment modalities.

Professor Rolls highlights the significance of exploring the brain-body connection, which has largely remained uncharted in scientific inquiry, particularly regarding functional anatomy. This study seeks to fill gaps in knowledge regarding how the brain influences disease emergence and the body's response to treatment. By identifying regions that are actively involved during different inflammatory states, they aim to create targeted interventions, possibly allowing for non-invasive therapies to combat autoimmune diseases.

The research could hold the key to discovering novel therapies that leverage the brain's neuroplasticity, enhancing immune functionality. In past studies, Prof. Rolls and her team revealed that positive expectations linked to the brain's reward system could significantly bolster immune responses. They also noted that the brain retains memory-like representations of previous inflammatory conditions in the insular cortex, suggesting a modulating role for this region in autoimmune responses.

Dr. Josh Schulman, Chief Scientist at Corundum Neuroscience, expressed enthusiasm for the project, emphasizing its potential to identify new targets for immunity optimization through translational science. The collaboration with Tel Aviv University through Ramot, the university's tech transfer company, signifies a robust commitment to advancing innovative research.

This initiative is particularly timely as the growing burden of autoimmune disorders necessitates fresh approaches in their management and treatment. With Corundum Neuroscience's resources and expertise, the research may lead to game-changing insights that reshape therapeutic strategies for patients afflicted with these conditions.

By supporting this groundbreaking research, Corundum Neuroscience reaffirms its dedication to transforming scientific discoveries into practical solutions that enhance human health and quality of life. The transition from lab to real-life applications is paramount, and with the awarded grant, the team at Tel Aviv University is poised to pave the way for more effective and non-invasive treatment options for autoimmune diseases.

For updates and additional details about Corundum Neuroscience and its research initiatives, interested parties can visit their website and follow their progress on LinkedIn.