#Italy #Vienna #neurosurgery #Esaote #I-Genius

Esaote Unveils Cutting-Edge Intraoperative MRI System: I-Genius

Esaote, a prominent name in medical imaging with deep roots in Italy, has taken a significant leap into neurosurgery by introducing the I-Genius, an avant-garde intraoperative MRI system. This groundbreaking system was showcased during the 25th European Association of Neurosurgical Societies (EANS) Annual Congress, held from October 5-9, 2025, in Vienna. The impressive collaboration between Esaote's research team and leading neurosurgeons led to the development of I-Genius, specifically designed to address the complex challenges faced during brain tumor surgeries.

The Challenge of Gliomas

Gliomas are classified as the most prevalent form of primary malignant brain tumors, constituting around 81% of all malignant intracranial tumors. Among them, glioblastoma is particularly concerning, accounting for approximately 45% of the cases and presenting a disheartening five-year survival rate of around 5%. Traditionally, the goal during surgery is to excise as much of the tumor as possible; however, differentiating tumor tissue from healthy brain tissue can be notoriously difficult with the naked eye, leading to a significant risk of leaving residual disease behind. Studies indicate that incomplete resection frequently leads to tumor recurrence.

To mitigate these risks, various imaging techniques are used to reveal remnants of the tumor. However, once the meninges are breached and particularly during tumor removal, the brain's position shifts, causing a misalignment between preoperative and intraoperative imaging. This disconnect can increase the chances of parts of the tumor being left behind. While methods like ultrasound and CT scans are commonly employed, they come with limitations. Ultrasounds have a limited field of view, and CT scans entail repeated exposure to ionizing radiation. In contrast, MRI technology presents a strong alternative but is often hindered by the constraints of previous intraoperative systems that are typically closed-magnet models—complex to operate during surgery and costly in terms of installation and maintenance.

The I-Genius Advantage

Esaote's I-Genius redefines this landscape with an innovative open MRI design optimized specifically for the needs of neurosurgical environments. It is accompanied by a specially designed surgical table and supporting accessories that are fully compatible with MRI operations. One of its major advantages is that the patient remains on the same table throughout the entire procedure without requiring any movement during the operation, allowing for efficient MRI image acquisition during surgery. This facilitates timely confirmation that tumor removal has been complete before the skull is closed, effectively minimizing surgical complexities and reducing the risks of having to perform a second surgery.

The I-Genius's potential was underscored during the Symposium titled "Expertise Meets Innovation: Why the I-Genius MRI Solution Will Change Neurosurgery," presented at the EANS Congress. Dr. Roberto Herrera, Chief of Neurosurgery at Clinica Adventista Belgrano, Buenos Aires, emphasized the significance of I-Genius. He stated, "What is truly innovative about I-Genius is its ability to provide intraoperative imaging at every stage of neurosurgery. It allows surgeons to remove the lesion, immediately verify the outcome, and make precise adjustments during the operation. This iterative process ensures maximum safe resection of the tumor while safeguarding the healthy brain and preserving the patient’s neurological functions."

Esaote’s Vision for the Future

Franco Fontana, CEO of Esaote, remarked on the significance of the I-Genius as a landmark advancement for the company, attributing it to a strategic focus on technological innovation, applied research, and close collaboration with the clinical community. He stated, "With this system, we are entering the intraoperative MRI field with a solution that is both accessible and sustainable—adding immense value to daily neurosurgical practice and enhancing patients' quality of life."

As a leader in medical imaging, Essaote employs approximately 1,300 individuals, half of them based in Italy, and invests about 13% of its consolidated sales into research and development each year. With facilities located in Genoa and Florence and its own production and research units in Italy and the Netherlands, Esaote continues to have an influential presence in over 100 countries worldwide.

For more information, visit Esaote's Official Website.