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World Precision Instruments Launches EVOM™ Chip

In a significant advancement for organ-on-chip (OOC) research, World Precision Instruments (WPI) has teamed up with SynVivo to introduce the EVOM™ Chip, a pioneering multiplex transepithelial electrical resistance (TEER) system. Launched at the MPS World Summit in Brussels, the EVOM™ Chip is a game-changer, enabling researchers to conduct real-time, non-destructive monitoring of barrier integrity in OOC models. This innovation comes as the OOC market continues to expand, encountering challenges around standardization and automation—crucial components for mainstream pharmaceutical research adoption.

Innovating TEER Measurements

The EVOM™ Chip is designed to facilitate multiplexed TEER measurements across multiple channels, offering unparalleled ease for researchers and drug developers. With embedded electrodes, this system allows continuous monitoring throughout the life cycle of the OOC platforms, providing invaluable insights from cell seeding to barrier formation and drug treatment processes. By delivering accurate and reproducible data without compromising the health of the cells, the EVOM™ Chip represents a leap forward in functional, scalable, and repeatable OOC sensing.

Mark Rutledge, CEO of WPI, highlights a crucial gap in existing technologies—the ability for on-chip, non-destructive TEER measurements. "This capability is demanded by most OOC platforms but has seldom been implemented successfully. The EVOM™ Chip fills that gap, making monitoring both effective and user-friendly,” he explains.

Collaborative Efforts Enhance Research Precision

WPI has a long-standing reputation as a leader in TEER technology, with its EVOM™ family of products supporting thousands of peer-reviewed publications globally. Collaborating with SynVivo amplifies this expertise by integrating TEER measurements directly into SynVivo's cutting-edge Blood-Brain Barrier (BBB) OOC model, enhancing data fidelity and reducing variability across experiments.

Gwen Fewell, CEO of SynVivo, comments on this collaboration: “Integrating TEER measurement into our chip not only streamlines experimental workflows but also improves the predictive accuracy of in vitro testing. This partnership offers a robust solution for our researchers tackling complex issues in central nervous system (CNS) studies, inflammation, and drug discovery.”

Future of Drug Development and Disease Modeling

Following the launch of the EVOM™ Chip, WPI and SynVivo plan to extend this technology to upcoming barrier tissue platforms, promising consistent, reproducible data essential for drug development and disease modeling. The standardization of TEER measurements across multiple platforms will facilitate reliable comparisons across various experiments and laboratories, ultimately enhancing the efficacy of drug development pipelines.

Those interested in seeing the EVOM™ Chip firsthand can visit WPI at Booth #131 and SynVivo at Booth #404 at the MPS World Summit from June 10-13, 2025, to learn more about the capabilities of this innovative technology.

About World Precision Instruments

With over 55 years of experience, World Precision Instruments stands as an influential global manufacturer and provider of innovative research equipment and supplies. Focused on life sciences, pharmaceutical, healthcare, and industrial markets, WPI is dedicated to equipping researchers with tools that enhance drug discovery, validate therapeutic mechanisms, and understand pharmacodynamics and safety.

About SynVivo

SynVivo is pioneering the development of physiologically relevant tissue models for various applications, including drug discovery and safety testing. Utilizing advanced microfluidic platforms, SynVivo replicates human tissue microenvironments to improve the prediction accuracy for in vitro studies, setting new standards in human-relevant drug development.