Celltrion Unveils Six Abstracts on IBD at 2025 Digestive Disease Week, Enhancing Clinical Insights
Celltrion's Presentation of IBD Abstracts at DDW 2025
Celltrion, a notable biopharmaceutical company based in South Korea, is set to highlight its contributions to the field of Inflammatory Bowel Disease (IBD) at the upcoming Digestive Disease Week® (DDW) 2025, scheduled for May 3-6 in San Diego, California. The firm has announced that six impactful abstracts will be presented during this prominent event, showcasing their ongoing commitment to advancing the understanding and treatment of IBD.
Focus on ZYMFENTRA®
Central to Celltrion's presentations is data regarding ZYMFENTRA® (infliximab-dyyb), which has been the first and only FDA-approved subcutaneous infliximab. This innovative therapy is used in the maintenance treatment of moderately-to-severely active ulcerative colitis and Crohn's disease. The clinical evidence presented will include post hoc analyses from their pivotal LIBERTY studies - vital research that continues to shape treatment paradigms for Crohn's disease and ulcerative colitis.
Dr. Hetal Patel, Vice President of Medical Affairs at Celltrion USA, expressed enthusiasm regarding these presentations. He emphasized that the data aims to reinforce ZYMFENTRA's clinical value to healthcare professionals and patients. With the complex and evolving nature of IBD management, these findings are expected to provide clarity on the drug's effectiveness across various patient demographics, aiding in decision-making processes for healthcare providers.
Key Presentations at DDW 2025
The abstracts accepted for the presentation cover a wide range of crucial topics for IBD management:
1. Endoscopic and Histologic Outcomes: This post hoc analysis from the LIBERTY-UC study evaluates patient responses to subcutaneous infliximab and is scheduled for a poster presentation on May 4.
2. Clinical Recapture After Dose Escalation: Another important analysis focuses on the timelines for clinical recapture following dose escalations in patients who experienced a loss of response, again from the LIBERTY trials.
3. Efficacy Based on Disease Location: One of the presentations will delve into how the maintenance therapy’s efficacy varies according to disease location in patients suffering from moderate-to-severe Crohn's disease.
4. Impact of Immunogenicity: An analysis studying the long-term clinical outcomes associated with immunogenic responses when patients are treated with subcutaneous infliximab.
5. Characterizing Loss of Response: A significant presentation that discusses patient profiles experiencing loss of response during maintenance therapy.
6. Nationwide Cohort Study: An examination of the use and persistence of both IV and subcutaneous infliximab in France, contributing further to the landscape of IBD patient management.
These presentations will not only unveil new insights into the long-term management strategies for IBD but will also represent Celltrion's ongoing commitment to providing healthcare professionals with comprehensive data needed to make informed treatment decisions in a challenging clinical landscape.
Conclusion: A Commitment to IBD Research
As IBD continues to affect millions globally, Celltrion's initiatives at DDW 2025 underline their dedication to improving treatment outcomes. By reinforcing the clinical value of ZYMFENTRA and sharing valuable real-world evidence, they aim to empower healthcare professionals and patients alike. With the growing need for individualized treatment methods in IBD, these insightful analyses are expected to play a pivotal role in shaping future clinical practices and patient care standards. The IBD community looks forward to the valuable knowledge to be shared at this major gastroenterology conference.
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