#Japan #Tokyo #Ipsa #Metabolism #Cellular Energy

Introduction

Ipsa has dedicated itself to uncovering the mechanisms of beauty for nearly four decades. The brand has been at the forefront of research in skin metabolism, focusing on how skin regenerates itself effectively. One of the fundamental components influencing this process is oxygen, which plays a critical role in cellular health and renewal. Recently, Ipsa has evolved its metabolism study by emphasizing adenosine triphosphate (ATP), the energy currency of the cell that is produced through the consumption of oxygen. This focus has highlighted the significant role of fatty acids alongside oxygen in maximizing cellular energy production. Additionally, a new extract, Koji Sour Extract, has been identified as a notable component that enhances energy production from both oxygen and fatty acids.

The Key to Beautiful Skin: Cellular Energy

Research shows that a continuous supply of energy is essential throughout the cellular maturation process to maintain epidermal health. By utilizing a 3D skin model, Ipsa discovered that inhibiting cellular energy production adversely affects not only the formation of a healthy epidermis but also the expression of vital proteins such as filaggrin and loricrin, which are crucial for hydration and barrier function. This finding has led Ipsa to position cellular energy as the cornerstone of beautiful skin, prompting further investigations into the mechanisms of energy production.

New Insights into Cellular Energy Production Mechanisms

1. The Importance of Fatty Acids in Energy Production

Expanding research into cellular energy mechanisms has unveiled new keys to achieving beautiful skin. The study revealed that energy sources utilized by cells change throughout their maturation process. In the basal layer, glucose serves as the primary energy source, while in the granular layer, approaching the completion of cellular maturity, the utilization of fatty acids significantly increases.

Fatty acids are pivotal in energy production pathways that utilize oxygen. When cells are subjected to low oxygen levels or fatty acid utilization is inhibited, energy production diminishes drastically. This reduction has a cascading effect on the expression of essential skin factors vital for skin maturation. Therefore, Ipsa believes that leveraging fatty acids as an energy source is crucial to realizing beautiful skin.

2. Discovery of Ingredients that Enhance Cellular Energy Production

After exploring around 200 different materials and ingredients, Ipsa discovered that Koji Sour Extract effectively enhances cellular energy production by facilitating the uptake of oxygen and fatty acids in epidermal cells. The patent application for this innovative process is currently underway.

Future Prospects

These discoveries bring us closer to understanding the mechanisms through which skin can unleash its innate potential. Ipsa is committed to continuing its exploration of the behavior of oxygen, water, and cellular energy to unlock the mysteries of life and beauty.

Notes:
1. Ipsa Official Website: Research on the relationship between beautiful skin and oxygen.
2. Filaggrin: A protein that serves as a natural moisturizing factor (NMF) essential for retaining moisture; Loricrin: A protein that strengthens barrier functions and moisture retention in skin cells.
3. Ipsa's philosophy regarding the final stage of cellular maturation that constitutes beautiful skin.
4. The amount of energy produced utilizing oxygen.
5. Japanese Patent Application No. 2023-149359.

About Ipsa

Ipsa is a subsidiary brand of Shiseido Co., Ltd. focused on skincare innovation.

Contact Information for Inquiries
PR Department, Ipsa Co., Ltd.
[email protected]
Address: 7-1-16 Akasaka, Minato-ku, Tokyo 107-0052
Phone: 03-3405-2432 (Direct PR Line)
Website: www.ipsa.co.jp