#Wound Care #Tiger BioSciences #Placental Allograft

Revolutionary Findings on Placental Allografts for Healing Complex Wounds

Groundbreaking Study on Placental Allografts

Recent research published in the Journal of Wound Care outlines the exceptional effectiveness of placental allografts in healing complex and chronic wounds. The study, conducted by a team at Tiger BioSciences, reflects a growing recognition of the serious implications chronic wounds can have on patients, with mortality rates that can rival those of certain cancers. These findings highlight the urgent need for effective treatment methods to enhance patient outcomes.

The Challenge of Chronic Wounds

Chronic wounds pose considerable health risks. Patients suffering from diabetic foot ulcers (DFUs) have a mortality risk that is five times higher than those with breast or prostate cancer. Moreover, nearly 50% of individuals undergoing limb amputation as a result of DFUs do not survive beyond five years. Venous leg ulcers (VLUs) also present significant challenges due to their slow healing process and susceptibility to rapid deterioration. This urgent reality underscores a critical need for innovative wound care solutions that not only promote healing but also prevent further complications like tissue damage and unnecessary surgical interventions.

Study Overview

The study involved a thorough assessment of 114 patients with an average age of 73.1, including 51 males and 63 females, and examined 184 different complex wounds. Patients received weekly applications of completeFT™, a dehydrated, full-thickness placental allograft, in conjunction with standard care. The remarkable results showcased a significant reduction in wound size across all examined categories:

- Diabetic Foot Ulcers (DFUs): 11 cases
- Venous Leg Ulcers (VLUs): 48 cases
- Pressure Ulcers: 73 cases
- Surgical Wounds: 13 cases
- Other Wounds: 39 cases

By the final application, 124 wounds exhibited a greater than 70% reduction in size. The study found that:

- 31.5% of wounds reduced by 60.3%–100% with 1–5 applications.
- 68.5% of wounds showed a reduction of 71.4%–98.3% following 6–10 applications.

Statistical significance was confirmed, illustrating that the treatment provided real, clinically beneficial results for patients across all categories.