#USA #Washington #Paralyzed Veterans #Journavx #Dr. Stephen Waxman

Groundbreaking Achievement in Pain Relief Research

The Paralyzed Veterans of America (PVA) proudly announces that Dr. Stephen Waxman, a long-time collaborator and researcher, has been awarded the prestigious 2026 Sharpey-Schafer Prize. This honor recognizes his extensive research into the molecular mechanisms of pain, highlighting his significant contributions towards developing the first non-addictive pain relief medications. The Sharpey-Schafer Prize, awarded by the UK-based Physiological Society every three years, acknowledges transformative contributions to physiology that advance both scientific understanding and public health.

Dr. Waxman, who leads the Center for Neuroscience and Regeneration Research at the Yale School of Medicine, has dedicated his career to understanding the intricacies of pain pathways, paving the way for innovative treatment options. His work has been vital in identifying specific molecules that play a crucial role in signaling pain, leading to new classifications of medications that can effectively treat pain without relying on traditional opioid mechanisms.

This honor is particularly timely as it follows the pioneering development of Journavx, the first new acute pain medication approved by the FDA in over two decades. This revolutionary treatment specifically targets pain signaling proteins found exclusively in the peripheral nervous system, providing an essential alternative for conditions relating to spinal cord injuries and diseases. While not yet approved for chronic pain management associated with issues like spinal cord injuries or degenerative diseases, the introduction of Journavx into the market represents a monumental milestone in pain management.

PVA's Commitment to Research

The PVA has played a pivotal role in this achievement, supporting Dr. Waxman and his team with over $9 million in research funding since 1976. This investment exemplifies PVA's enduring commitment to enhancing the quality of life for veterans suffering from spinal cord injuries or diseases such as multiple sclerosis and amyotrophic lateral sclerosis (ALS). The organization’s National President, Robert Thomas, emphasized the importance of such research endeavors not only for veterans but also for individuals dealing with acute pain across the nation.

"For nearly 80 years, PVA has been a champion for essential research that enhances the lives of Veterans with spinal cord injuries and diseases," Thomas noted. "This prestigious award is a powerful reminder that investing in such scientific research can yield life-changing results for our community, allowing disabled Veterans and all individuals dealing with pain to lead richer, more active lives."

Since its inception, PVA has funded 644 research grants totaling over $54 million, which has included backing for clinical trials, comprehensive laboratory studies, the development of innovative health technologies, and fellowships designed to foster new medical research. Additionally, PVA facilitated the establishment of the Yale Center for Neuroscience and Regeneration Research, which continues to drive cutting-edge studies to this day.

Future Directions

Dr. Waxman expressed gratitude for PVA’s critical support, indicating that their partnership has been instrumental in obtaining such significant scientific accolades. He remains hopeful as he focuses on future research efforts aimed at discovering new treatments — and ideally, cures — for spinal cord injuries and diseases. "The Sharpey-Schafer Prize underscores the mutual commitment between our teams, and I eagerly await the day we can celebrate a complete victory together," Dr. Waxman stated.

With ongoing efforts and significant advancements in the medical field, PVA continues to encourage its community to learn more about its research initiatives and explore opportunities for funding via PVA's Research Foundation. Interested parties can visit PVA.org/ResearchFoundation to discover how they can contribute to this vital cause and learn about available grants.

About Paralyzed Veterans of America

Paralyzed Veterans of America is a non-profit organization dedicated exclusively to the representation and benefit of veterans with spinal cord injuries or diseases. PVA's mission encompasses ensuring that veterans receive their entitled benefits, overseeing their care in VA spinal cord injury units, and promoting education and research aimed at finding cures and improving care standards for those affected by paralysis.

Their robust outreach includes providing training and career services, advocating for accessibility in public spaces, and facilitating health and rehabilitation opportunities through sports and recreational programs. With over 70 offices and 33 chapters, PVA is committed to serving veterans, their families, and their caregivers throughout all 50 states, the District of Columbia, and Puerto Rico.