#Canada #Toronto #Drug Discovery #Xtalks #DEL Technology

Advancements in Small Molecule Drug Discovery

The landscape of drug discovery is undergoing a transformative phase with the emergence of DNA-Encoded Library (DEL) technology. This powerful tool significantly accelerates the process of identifying potential hits for small-molecule drugs, paving the way for more effective treatments.

Join the Upcoming Webinar

On September 22, 2025, Xtalks is hosting a free webinar designed to equip attendees with key insights into DEL technologies. This session will cover both non-covalent and covalent DEL platforms, showcasing how these innovations can boost early-stage drug discovery workflows. Participants can expect to gain valuable knowledge about the core principles of DEL technology, recent advancements, and practical strategies to apply these resources in their research.

The webinar will feature Alex Shaginian, Vice President of Business Development and Chemical Sciences at HitGen. With a wealth of experience in the industry, Shaginian will bring a deep understanding of the potential of DEL technologies in addressing critical challenges in drug discovery. He will share success stories that demonstrate how DEL tools can identify hits against difficult biological targets.

Understanding DEL Technology

DEL technology streamlines the identification of small molecules by employing large libraries of DNA-encoded compounds. These libraries facilitate the rapid screening of vast chemical spaces, greatly enhancing the chances of discovering fruitful candidates during the early phases of drug development. This methodology not only saves time but also reduces the cost associated with traditional drug discovery processes, making it a game-changer in the pharmaceutical landscape.

Recent Developments in DEL

The upcoming webinar will begin with an overview of DEL technology, emphasizing its foundational principles. Following that, it will delve into recent developments in non-covalent DNA-Encoded Libraries. Attendees will learn about novel on-DNA chemistry methods that broaden accessible chemical spaces and explore how these innovations are being applied to tackle challenging drug targets.

Additionally, the discussion will include a detailed analysis of covalent DEL platforms. Shaginian will present a compelling case study that illustrates how selective covalent inhibitors can be identified effectively using these platforms, further showcasing the versatility and impact of DEL technology.

Fragment-Based Drug Discovery and DEL

An interesting facet of the webinar will focus on the burgeoning relationship between DEL technology and fragment-based drug discovery (FBDD). This cross-disciplinary approach is gaining traction, combining strengths from both methodologies to enhance hit identification strategies. By leveraging the strengths of both DEL and FBDD, researchers can expand their arsenal in tackling challenging targets, ensuring a more robust pipeline of potential therapeutic options.

Registration and Participation

Attendees are encouraged to register for this enlightening session as it promises to provide crucial insights into how cutting-edge DEL technologies can revolutionize small molecule drug discovery. The integration of efficient and transparent small molecule screening platforms into research workflows will also be discussed, emphasizing both accessibility and efficacy.

Join us for this invaluable opportunity to learn from industry experts and discover how DEL technology is shaping the future of drug discovery. For more details and to register, visit the Xtalks website.

About Xtalks

Xtalks, powered by Honeycomb Worldwide Inc., serves as a premier platform for educational webinars and digital content tailored for professionals in the life sciences, food, healthcare, and medical device sectors. Yearly, they draw thousands of industry practitioners eager to stay ahead of trends, regulations, and job opportunities. Their webinars feature leading voices in the industry, tackling pivotal issues and sharing insights from top thought leaders.

For more information about Xtalks and their offerings, you can visit their website at Xtalks.com.