Ginkgo Bioworks Integrates Modular Automation to Enhance Microbial Research at PNNL

Ginkgo Bioworks, recognized for its innovative contributions in cell programming and biosecurity, has made headlines with its latest deployment of state-of-the-art automation technology at the Environmental Molecular Sciences Laboratory (EMSL) located at Pacific Northwest National Laboratory (PNNL) in Richland, Washington. This initiative aims to accelerate research into microbes that are essential to the bioeconomy, reflecting both organizations' commitment to pioneering advances in this scientific field.

Under a significant $4.66 million contract, Ginkgo will install an advanced automated platform equipped with its Reconfigurable Automation Carts (RACs) technology. This technology is designed to enhance laboratory efficiency and throughput while maintaining low operational overheads. The integrated workcell consists of 18 sophisticated devices within a modular anaerobic chamber, allowing for more streamlined experimental workflows.

The partnership will enable EMSL scientists to conduct ambitious microbial research in an efficient manner, leveraging the flexibility and capabilities of Ginkgo’s automation. By allowing for remote operation of various complex end-to-end anaerobic phenotyping workflows, researchers at EMSL will be better equipped to pursue critical investigations into biological phenomena relevant to energy production and supply chain resilience.

Ginkgo's automation system is built on a modern, web-based software architecture that supports programmatic control through API access. This setup not only facilitates seamless integration of advanced laboratory equipment but also empowers researchers to capitalize on AI-driven methods, further enhancing the discovery process. The goal is to foster scenarios where researchers can transition toward fully autonomous workflows, significantly expediting the exploration of new biological insights.

Will Serber, General Manager of Ginkgo Automation, expressed enthusiasm regarding this collaboration, stating that their technology is tailored to support the ambitious research objectives set by EMSL. He emphasized the value of automation in promoting scientific inquiry while maintaining researchers' control over their experimental processes.

The deployment of this automation platform is timely, promising to be fully operational later in the year. As Ginkgo’s technology enables EMSL to advance its research in microbial engineering and biodesign, it also sets the stage for potentially transformative public-private partnerships in the biotechnology sector. With the global emphasis on bioeconomy, such innovations are crucial for advancing the frontiers of bioengineering and sustainability.

Ginkgo Bioworks is not just a pioneer in automation; they are also positioned to provide customizable research and development packages, including advancements in protein engineering and nucleic acid design. By selling integrated laboratory solutions that allow scientists to focus on data analysis rather than routine pipetting, Ginkgo continues to redefine the landscape of modern scientific research. The company’s commitment extends beyond just science; it encompasses biosecurity initiatives—aiming to help organizations predict and mitigate a wide array of biological threats.

In conclusion, Ginkgo Bioworks’ partnership with PNNL to deploy modular automation technology at EMSL marks a significant milestone in microbial research. This collaboration not only aims to enhance laboratory processes but also seeks to establish a robust framework for innovation in the bioeconomy, with substantial implications for energy production and material resilience. Through this partnership, Ginkgo remains committed to supporting cutting-edge research that can influence global biotechnological advancements.

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