#USA #Columbus #CAS #Cleveland Clinic #Alzheimer’s Disease

A Groundbreaking Collaboration Between CAS and Cleveland Clinic

In a significant advancement for clinical research, CAS, a division of the American Chemical Society, has teamed up with Cleveland Clinic, a well-renowned academic health system, to accelerate research through cutting-edge technologies like artificial intelligence (AI) and quantum computing. This partnership aims to push the boundaries of health and wellness research, particularly focusing on the complexities of brain health and the treatments for conditions such as Alzheimer’s disease, where effective therapies are currently scarce.

The Initiative's Dual Focus

The collaboration was officially announced during the Cleveland Discovery and Innovation Forum, a prestigious event showcasing groundbreaking research in health and life sciences. The initial phase of their joint efforts will concentrate on drug discovery related to brain health, a critical area given the prevalence and complexity of Alzheimer’s disease.

Dr. Lara Jehi, the Chief Research Information Officer at Cleveland Clinic, emphasized the synergy between both organizations, stating, "This unique collaboration leverages Cleveland Clinic's expertise in biomedical research and clinical care alongside CAS's leadership in scientific data and technology. Together, we aim to generate high-quality medical data, validate scientific models, and integrate research to ultimately enhance patient care and chronic disease treatment."

Innovative Technology Applications

One of the core resources that will be utilized in this initiative is the CAS Content Collection™, recognized as the most comprehensive curated collection of scientific information globally. Combined with advanced technologies, including new AI models and quantum computational methods, this collaboration presents a promising future for medical research.

Cleveland Clinic houses an IBM Quantum System One as part of its strategic partnership with IBM, representing the world's first quantum computer dedicated solely to health research. This partnership will enable the development and training of disease-specific models, starting with Alzheimer’s, ultimately transitioning to preventative strategies and predictive applications for various chronic diseases.

Bridging the Research Gap

Manuel Guzmán, President of CAS, commented on the long-standing challenge of translating scientific discoveries into practical therapies, noting that it typically takes 17 years for lab breakthroughs to culminate in approved treatments. "We believe that our collaboration will help bridge this gap. United by a common goal of improving lives through scientific innovation, we will combine high-quality content, subject matter expertise, and advanced technologies to uncover new pathways towards healthy aging and generate significant social and economic impact," he stated.

The collaboration will also capitalize on the Cleveland Innovation District's collaborative environment, which brings together state entities and leading health and education institutions in Cleveland. This initiative aims to foster job creation, enhance research outputs, and cultivate the workforce of the future in the health sector.

CAS and Cleveland Clinic

About CAS

CAS connects global scientific knowledge to accelerate advances that enhance lives. By helping innovators navigate the complex data landscape, CAS enables informed decision-making during all stages of the innovation process. Known for its scientific knowledge management expertise, CAS boasts the world’s largest authorized collection of scientific data and offers essential information services and solutions. Across various sectors, scientists, patent professionals, and business leaders rely on CAS to discover opportunities, mitigate risks, and unlock shared knowledge to expedite the journey from inspiration to innovation.

About Cleveland Clinic

Cleveland Clinic is a nonprofit, multidisciplinary academic medical center that integrates clinical practice with research and education. Founded in 1921, it was created by four renowned physicians committed to delivering exceptional patient care grounded in cooperation, compassion, and innovation. Cleveland Clinic has pioneered numerous medical breakthroughs including coronary artery bypass surgery and the first face transplant in the US. Consistently recognized nationwide and globally for excellence in care, Cleveland Clinic employs over 81,000 professionals, including more than 5,743 physicians and researchers and 20,160 registered nurses across 140 specialties and subspecialties. The health system comprises a 6,690-bed network, which includes a main campus near downtown Cleveland, 23 hospitals, and 276 outpatient clinics, not just in Ohio, but also extending to Florida, Las Vegas, Toronto, Abu Dhabi, and London. In 2023 alone, Cleveland Clinic recorded approximately 13.7 million outpatient visits, over 323,000 hospital admissions, and 301,000 surgeries and procedures across its healthcare network.