#United States #Emeryville #Flow Cytometry #Slingshot Bio #ViaComp Ultra Amine

Slingshot Bio Unveils ViaComp® Ultra Amine for Enhanced Flow Cytometry Controls

Emeryville, California-based Slingshot Bio, Inc., renowned for its pioneering advancements in precision cell mimic controls for flow cytometry, has launched ViaComp® Ultra Amine, a revolutionary next-generation compensation control designed specifically for amine-reactive viability dyes and fluorophore-conjugated antibody panels in both spectral and traditional multiparameter flow cytometry workflows.

About ViaComp® Ultra Amine

ViaComp® Ultra Amine serves as a game-changer in the realm of flow cytometry controls, enabling significant advancements in spectral unmixing and compensation across intricate, multiparameter workflows. Its innovative design facilitates simultaneous capture of amine-reactive viability dyes and antibodies from multiple host species—such as mouse, rat, hamster, rabbit, and human—using a single, versatile reagent.

Each unit comes as a ready-to-use dropper containing a pre-mixed suspension of positive and negative control particles. This design ensures clear, distinctly separated peaks when analyzing the fluorescence spectrum of the respective dye or fluorophore, streamlining workflows and saving precious time for researchers.

Revolutionizing Flow Cytometry Workflows

In the words of the Slingshot Bio Scientific Team, “ViaComp® Ultra Amine represents a meaningful advancement in how flow cytometry labs approach viability and compensation controls. By combining amine-reactive viability dye capture with multi-species antibody capture in a single liquid, non-biohazardous reagent, we eliminate a significant variation source and greatly simplify the compensation process.”

Control processes in flow cytometry are integral throughout various stages of assay development—from instrument setup to panel optimization and inter-site harmonization. Traditional biological controls, typically involving cell lines, donor-derived PBMCs, and polystyrene beads, have often posed issues like lot-to-lot variability, resource intensity, and regulatory burdens. ViaComp® Ultra Amine aims to rectify these challenges by blending the biological significance of cell-based controls with the precision and scalability characteristic of semiconductor manufacturing.

The product represents the latest addition to Slingshot Bio's expanding portfolio, which includes various advanced controls like SpectraComp®, ViaComp®, FlowCytes®, PhenoCytes™, and ScatterBridge®—all geared towards enhancing instrument standardization, compensation protocols, cell health analysis, biomarker control, and cross-site harmonization.

Product Features and Benefits

Enhanced Features:

• - Single Control: Facilitates comprehensive panel compensation workflows.
• - Broad Compatibility: Works seamlessly with amine-reactive viability dyes and fluorophore-conjugated antibodies.
• - Multiple Species Capture: Integrates antibody captures from species including mouse, rat, hamster, rabbit, and human.
• - Cell-like Profiles: Provides realistic scatter and autofluorescence patterns.
• - Improved Separation: Demonstrates superior positive/negative separation compared to previous ViaComp versions.
• - User-Friendly Format: Offered in a liquid, non-biohazardous format, with 2–8°C storage, making it easy to use.
• - No Preparation Needed: Ready-to-use dropper format eliminates preparation hassles.

In testing, the ViaComp® Ultra Amine demonstrated consistent performance across a 36-color spectral panel on multiple instruments, providing the reliability and flexibility required for cross-site harmonization studies, affirming its importance to researchers.

Availability

The ViaComp® Ultra Amine is now accessible for order through Slingshot Bio's commercial catalog, part of the newly launched ViaComp® Ultra product line, which includes ViaComp® Ultra DNA. Manufactured under ISO 9001 quality management standards, it is intended for research purposes only.

Slingshot Bio presented ViaComp® Ultra Amine alongside its diverse cell mimic platform at the CYTO 2026 event, where an informative tutorial titled, “Cell Mimics as Cross-Platform Controls Advancing Compensation, Viability, and Biomarker-Specific Assays in a 36-Color Spectral Panel Across Multiple Instruments,” was delivered by seasoned members of the Field Application Science Team.

About Slingshot Bio

Founded in Emeryville, California, Slingshot Bio, Inc. is a groundbreaking life science company that specializes in the creation of innovative cell mimic controls tailored to improve flow cytometry procedures. Their patented technology merges advanced semiconductor manufacturing standards with biologically relevant particle design, promising researchers scalable, reproducible, and customizable solutions across all stages of flow cytometry workflows.

For more information, visit www.slingshotbio.com or contact Joshua Haydon at +1 510 770 6806 or [email protected].