#United States #Boston #Atraverse Medical #AF Symposium #HOTWIRE

Advancements in Cardiology: HOTWIRE™ System by Atraverse Medical

Atraverse Medical is at the forefront of innovative medical technology, particularly in the realm of cardiology. At the recent AF Symposium 2026 held in Boston, the company showcased exciting new clinical and preclinical data that emphasizes the efficacy and safety of its HOTWIRE™ Transseptal Access System.

Safe and Efficient Left Atrial Access

The core of Atraverse Medical's innovation, the HOTWIRE™ Transseptal Access System, has been designed to minimize the risk of unintended left atrial injury during procedures. The latest findings from three presentations made at the symposium highlighted the technology's performance, demonstrating its ability to reduce unintended tissue injury while maintaining a low radiofrequency (RF) duration.

One notable study, presented by Dr. Jeremiah Wasserlauf, MD, illustrated that the use of HOTWIRE™'s large-electrode technology, in conjunction with an impedance-guided RF generator, resulted in zero unintended left atrial injury events. This marked a significant improvement over previous small-electrode RF guidewire systems which reported injury cases exceeding 50% in similar models. Furthermore, the study showcased a substantial decrease in RF delivery time and total energy exposure to surrounding tissues.

Multicenter Observational Insights

The HOTWIRE™ system's capabilities were further validated through a multicenter, first-in-human observational study. Dr. Devi Nair, MD, showcased how this technology not only provided consistent and safe performance across a variety of procedures but also enhanced workflow efficiency. During the study, which involved around 500 patients, the HOTWIRE™ system achieved an impressive 100% procedural success rate. This resonates well with its design goals, emphasizing a simplified workflow with reduced RF duration and energy delivery necessary for successful procedures.

A Game-Changer in Transseptal Procedures

The system's significant effectiveness was reiterated in another presentation by Dr. Nair, which detailed over 1,000 transseptal procedures, maintaining a stellar 100% procedural success rate across different operator workflows and introducer sheaths. Notably, 29% of these procedures were executed using a zero-fluoroscopy approach, underlining the system's versatility in various clinical settings. No adverse events were recorded, emphasizing the device's safety.

Dr. Steven Mickelsen, Co-Founder and Chief Translational Science Officer of Atraverse Medical, emphasized the clinical importance of controlled RF delivery and the advanced impedance-guided shutoff feature of the HOTWIRE™ system, which halts energy delivery upon transseptal crossing. This enhances patient safety by mitigating the risk of unnecessary RF exposure in the left atrium.

The Future of Cardiovascular Procedures

What sets the HOTWIRE™ apart is its unique blend of a next-generation RF generator and a zero-exchange RF guidewire. This cutting-edge design optimizes transseptal access while enhancing workflow and improving patient outcomes. The HOTWIRE™ system's universal sheath compatibility and advanced design, which includes a proprietary tip architecture for improved echocardiographic visualization, mark a significant evolution in medical device technology.

Atraverse Medical, based in San Diego, CA, is committed to pioneering innovations in left-heart access and optimizing RF technology. Founded by Dr. Steven Mickelsen and his team, this company continues to lead the charge in improving techniques for treating cardiovascular diseases, ultimately aiming to enhance outcomes for millions of patients globally.

In conclusion, the new data presented at AF Symposium 2026 not only validates the HOTWIRE™ system's clinical value but sets a benchmark for future developments in cardiology devices. As Atraverse Medical continues to innovate, the capabilities of the HOTWIRE™ system promise to redefine safety and efficacy in cardiac procedures.