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Volta Labs Reveals 2025 Application Roadmap for NGS Sample Preparation

At the recently held Advances in Genomics and Biotechnology (AGBT) conference, Volta Labs, a prominent player in the genomics application field, took a major step by revealing its strategic plan for 2025 centered on next-generation sequencing (NGS) sample preparation. The company announced an exciting expansion of its Callisto App menu that will now encompass RNA library preparation, along with single-cell preparation and multi-sequencer capabilities.

Key Focus Areas for 2025

In 2025, Volta Labs will concentrate on four main objectives designed to enhance the efficiency and accessibility of genomic workflows. These priorities include:

1. Comprehensive Library Preparation: Launching advanced DNA, RNA, and single-cell preparation solutions tailored for laboratories of all sizes.
2. Cost-Effective Sequencing: Enabling laboratories to perform whole genome sequencing swiftly and economically.
3. Reducing Re-Do Rates: Focusing on minimizing the instances where sequencing needs to be repeated for targeted workflows.
4. All-in-One Solution: Offering a seamless one-stop platform for both long and short read preparations.

According to Abdul Mohammed, the founding scientist and head of product at Volta Labs, "I’m thrilled to be able to share our Application Roadmap for NGS Sample Prep for the first time at AGBT with the genomics community. The positive results we have observed from our customers demonstrate how Callisto Apps are aiding clinical labs in achieving consistent and cost-efficient whole genome sequencing with major players like Illumina and PacBio."

Innovations in Callisto App

The enhancements in the Callisto App are designed to deliver a full suite of support for both existing users and prospective clients. This includes rolling out applications that extend across:

• - Total RNA
• - mRNA library preparations
• - Single-cell library preparations
• - Support for sequencers from Element AVITI and Oxford Nanopore

Existing users of the Callisto App will automatically receive these updates through software enhancements. To complement these expansions, Volta Labs will also introduce application-specific kits that incorporate reagents alongside all necessary plastics for running the workflows effectively.

Application Launch Timeline

Currently available Volta Apps include:

• - DNA Library Prep for Illumina
• - PacBio SMRTbell 3.0 Library Prep
• - High molecular weight DNA extraction
• - DNA extraction for short-read sequencing
• - Hybridization Capture for IDT xGEN
• - Double-sided Size Selection

Anticipated app launches scheduled for this year include:

• - Total RNA Library Prep for Illumina
• - 10x Genomics 3' Gene Expression Library Prep
• - Oxford Nanopore Ligation-based Library Prep
• - Hybridization Capture for Twist
• - DNA Library Prep for Element sequencers

A New Era for Genomic Innovation

The Callisto Sample Prep System leverages advanced electrowetting technology that allows for precise control over droplets through electric and magnetic manipulation of liquids on an open surface. This innovative system promises to not only improve the results of sequencing processes but also reduce costs while ensuring user-friendliness. This development stands to unlock new possibilities for innovation within the genomics landscape.

As part of their ongoing commitment to assisting laboratories, Volta Labs invites stakeholders to learn more about the Callisto system and how it can transform NGS sample preparation during their visit to Lanai Suite 192 at AGBT.

About Volta Labs

Volta Labs continues to revolutionize genomics through innovation, providing users with easy-to-use sample prep solutions that help streamline workflows and improve sequencing outcomes. Their mission remains focused on supporting the genomics community through consistent advancements in technology and applications.

Stay updated on future innovations and breakthroughs from Volta Labs by visiting VoltaLabs.com.