Volta Labs Launches Automated Oxford Nanopore Library Prep App for Callisto to Enhance Sequencing Efficiency
Volta Labs, a pioneer in genomics applications, has taken a significant leap forward in DNA sequencing technology with the recent launch of their Library Prep App specifically designed for the Oxford Nanopore LSK114. Available on the Callisto™ Sample Prep System, this app marks a pivotal advancement in long-read sequencing capabilities.
This new technology not only enhances throughput by allowing flexible batching in sequencing workflows but also increases efficiency, freeing up valuable time for laboratory professionals to focus on other critical projects. With its automated processes, the application stands to support a variety of academic research and clinical projects, facilitating reliable library preparation for those utilizing Oxford Nanopore sequencing technology.
Technical features of the Library Prep App include complete automation that maintains DNA integrity throughout the preparation process. By utilizing Callisto’s unique digital fluidic architecture, the app also ensures cost-effectiveness through miniaturized reactions. Early-access partners have observed notable enhancements in both the efficiency of processes and the quality of the resulting libraries prepared using the LSK114 workflow.
According to Udayan Umpathi, founder and CEO of Volta Labs, “We are thrilled to bring this new app to the Oxford Nanopore community. It builds on the success we’ve achieved with our PacBio HiFi automation, furthering our mission to streamline single-molecule sequencing applications on a broader scale. The integration of Oxford Nanopore technology with Callisto's innovations is truly groundbreaking.”
Abdul Mohammed, Head of Product at Volta Labs, highlighted the importance of this release, stating, “The genomics community has been awaiting more accessible automation for long-read library preparation protocols. Our LSK114 app delivers just that—labs can now scale their Oxford Nanopore sequencing efforts without navigating the complexities traditionally associated with automation or sacrificing library quality.”
The app’s compatibility with the Callisto's 24-sample throughput aligns seamlessly with the capabilities of the PromethION 24 device, further emphasizing the app’s utility in high-throughput sequencing applications. As of now, the Library Prep App for Oxford Nanopore LSK114 is available as a software update for existing Callisto users and will be included in all new installations. The application collaborates with specially optimized reagents kits for the Callisto platform, assuring consistent performance and coherence in ordering processes.
Volta Labs has established itself as a leader in the field of genomic applications, with a focus on creating a cutting-edge digital fluidic platform that maximizes both performance and scalability in sample preparation while ensuring unparalleled consistency. The Callisto Sample Prep System is intended solely for research purposes, reinforcing Volta's commitment to advancing genomics through innovative solutions.