Complete Genomics Launches Revolutionary Sequencers at AGBT 2025 Meeting

At the 2025 Advances in Genome Biology and Technology (AGBT) General Meeting, Complete Genomics, a recognized leader in genomic sequencing technology, introduced its latest high-performance sequencing solutions: the DNBSEQ-T1+ and DNBSEQ-E25 Flash. These innovations promise to enhance the capabilities of researchers by facilitating quicker access to high-quality genomic data.

DNBSEQ-T1+: A Leap Forward in Mid-Throughput Sequencing


The DNBSEQ-T1+ is a state-of-the-art mid-throughput sequencer capable of completing a paired-end 150 sequencing workflow in a remarkable 24 hours, achieving Q40 accuracy. This phenomenal performance is made possible by various advanced features, including three flow cell formats and dual independent flow cell operation. With a throughput range of 25 to 1,200 Gb and a maximum capacity exceeding 1 Tb per day, laboratories can achieve faster turnaround times, which is critical in diverse research environments.

The integrated auto-DNB making and loading capabilities enhance user experience, allowing labs to manage multiple samples independently without the need for barcodes. The user-friendly design translates to a workflow that can be initiated in under ten minutes, minimizing the required hands-on time. Rob Tarbox, VP of Product and Marketing at Complete Genomics, highlighted, "The DNBSEQ-T1+ revolutionizes mid-throughput sequencing by combining high output with competitive pricing, accommodating a range of applications including Whole Genome Sequencing, Single Cell analysis, and oncology research."

With internal design optimizations, the DNBSEQ-T1+ significantly reduces the amount of reagents needed for sequencer operation, thus lowering the cost per GB. This advancement democratizes access, enabling smaller and mid-sized labs to utilize technology that was once exclusive to production-scale facilities. The DNBSEQ-T1+ is now available for global pre-orders.

DNBSEQ-E25 Flash: Portable Sequencing with AI-Powered Speed


Taking a significant leap in portable sequencing, the DNBSEQ-E25 Flash is an upgraded version of the existing DNBSEQ-E25 sequencer. It integrates advanced AI-driven capabilities with self-luminescence technology and a CMOS-based flow cell. This next-generation sequencer utilizes AI-optimized protein engineering to significantly enhance signal intensity and precision, allowing for a remarkable sequencing experience.

By featuring AI-supported base calling on an edge device powered by the NVIDIA Jetson platform, the DNBSEQ-E25 Flash accelerates the sequencing process to record levels. Traditional lengthy dual-luciferase systems have been replaced, enabling exceedingly fast single-substrate injections. Consequently, cycle times are reduced to a mere one minute, facilitating SE50 sequencing in less than two hours, which could redefine the future of portable sequencing technology.

Engage with Complete Genomics at AGBT 2025


Complete Genomics is set to host multiple activities at AGBT 2025 to celebrate the launch of these groundbreaking products. Attendees will have opportunities to witness live demonstrations and attend insightful presentations in Suite Osprey 6, alongside a workshop at Bronze 4 discussing advancements in genomic discoveries powered by the DNBSEQ-T1+.

One of the highlights includes a discussion led by Jason Fenwick from NVIDIA, focusing on benchmarking Parabricks workflows on DNBSEQ platforms. Demonstrations will showcase the seamless integration of GPU acceleration in genomic data analysis. The workshop will also feature Dr. Piotr Mieczkowski from UNC Chapel Hill, who will delve into the applications of DNBSEQ technology across various research domains.

For more details on the full AGBT 2025 agenda, participants are encouraged to visit the official website at www.completegenomics.com/agbt2025.

About Complete Genomics


Since its inception in 2005, Complete Genomics has been at the forefront of developing high-throughput, economically viable sequencing technologies. Boasting over 9,400 publications showcasing its innovative contributions, the company continues to propel genomic research globally forward.

Note: For research purposes only. Not applicable for diagnostic use.

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