#Sweden #Uppsala #OMNI #Navinci #spatial interactomics

Navinci Unveils Revolutionary Omni Kit for Transforming Protein Studies in Research

Navinci Launches the Omni Kit: A New Era in Spatial Interactomics

In a significant advancement for protein research, Navinci has officially introduced the Omni kit, a state-of-the-art tool poised to revolutionize how scientists explore protein functions directly in tissues. This innovative kit promises to enhance the understanding of protein functions, disease mechanisms, and therapeutic drug interactions.

What is the Omni Kit?

The Omni kit stands out due to its fully customizable nature, allowing researchers to tailor experiments to their specific needs. It is built upon Navinci’s proprietary in situ proximity ligation assay (isPLA) technology, which enables the simultaneous detection of up to nine target protein pairs in a single experiment. The uniqueness of this technology lies in its use of antibody-oligonucleotide partnerships. When these antibodies are in close proximity, they generate amplifiable DNA, helping researchers decipher protein-protein interactions, post-translational modifications, and specific protein targets all within the native tissue environment.

Customization and Versatility

To accommodate a range of research requirements, scientists can leverage Navinci’s extensive library of validated targets or opt for pre-validated panels focusing on critical research areas such as MAPK signaling, immuno-oncology, and TCR/BCR immune profiling. This flexibility facilitates quicker setup and more accurate experimental results as researchers won’t have to spend extensive time optimizing conditions.

Accessibility for the Research Community

Understanding that accessibility is crucial, Navinci offers the Omni kit as a ready-to-use kit suitable for in-house experiments. Additionally, it provides a full-service option conducted by Navinci experts, ensuring that research teams can harness the benefits of elite scientific tools regardless of their resources.

Proven Effectiveness

Following a partnership with Uppsala University, a proof-of-concept study was conducted that confirmed the Omni kit’s superior sensitivity and specificity across various cell lines and clinical FFPE samples. This capability enables simultaneous analysis of nine target pairs in one assay, affirming the kit's robustness and effectiveness (further details can be found in the pre-print study on Navinci's website).

High Multiplexing and Spatial Resolution

What truly sets the Omni kit apart is its ability to combine high multiplexing capabilities with exceptional performance and spatial resolution. This enables scientists to capture complex biological interactions in their native environment without sacrificing sensitivity or specificity.

Conclusion

The launch of the Omni kit marks a new milestone in spatial interactomics. By enabling deeper insights into protein interactions, it opens pathways for advancements in health research and drug discovery. For researchers eager to explore a revolutionary way to conduct protein studies, the Omni kit represents an indispensable addition to their experimental toolkit.

To learn more about the Omni technology, visit Navinci’s official website. Interested researchers can get started with Omni through Navinci's ordering page.