#USA #Milford #Waters Corporation #Mass Spectrometry #Xevo TQ

Waters Unveils the Xevo TQ Absolute XR Mass Spectrometer

On June 2, 2025, at the 73rd ASMS Conference on Mass Spectrometry, Waters Corporation (NYSE: WAT) proudly introduced the Xevo TQ Absolute XR, a groundbreaking mass spectrometer setting a new benchmark in sensitivity and robustness for high-performance laboratories. This innovative system is poised to transform analytical capabilities in sectors like pharmaceuticals and environmental testing, especially in responding to the growing needs associated with PFAS analysis.

Enhancing Performance

The Xevo TQ Absolute XR mass spectrometer emerges as the most sensitive and reliable benchtop tandem quadrupole model from Waters. With an extraordinary performance capability, the XR model offers up to a six-fold enhancement in robustness compared to its predecessor, the Xevo TQ Absolute. This significant advancement in performance is tailored for laboratories that require meticulous trace-level analysis in complex matrices, maximizing operational uptime and efficiency.

James Hallam, the Vice President of Liquid Chromatography-Mass Spectrometry at Waters, emphasized, “Analytical laboratories face increasing pressures to adapt to the complex demands from pharmaceutical organizations while addressing the rising need for PFAS analysis against a swiftly changing regulatory backdrop. The Xevo TQ Absolute XR’s performance delivers unrivaled sensitivity and contamination resilience, significantly reducing downtime and enhancing operational efficiency.”

Sustainable and Efficient Design

One of the most compelling features of the Xevo TQ Absolute XR is its commitment to sustainability. This state-of-the-art mass spectrometer utilizes up to 50% less energy and gas nitrogen, produces 50% less heat, and requires 50% less benchtop space than comparable high-performance tandem or triple quadrupole instruments available in the market. The innovative design not only minimizes environmental impact but also supports labs focusing on productivity without compromising performance.

Advanced StepWave XR Technology

The introduction of the StepWave XR Ion Guide technology within the Xevo TQ Absolute XR significantly reduces the chances of unexpected downtime while maintaining high sensitivity and accuracy, even for the most delicate sample types and compounds. With such advancements, laboratories achieve a new level of robustness across various applications, including PFAS testing, bioanalysis, and genotoxic impurity screening.

As stated by Sally Hannam, the Chief Scientist at Synexa Life Sciences, a leading provider of biomarker and bioanalytical services, “Our laboratory requires instrumentation that delivers high-quality results without disruptions to our clients, enabling them to bring new safe and effective drugs to market quickly. We have successfully surpassed 20,000 analyses of collapsed human plasma injections, showing unprecedented reproducibility and precision, thereby increasing our confidence in tackling progressively complex bioanalytical applications.”

Industry-Leading Quantification

Moreover, the Xevo TQ Absolute XR supports ready-to-use, industry-leading quantification of negative ionization compounds like PFAS. This capability is vital for bioanalysis, food safety, and environmental laboratories seeking reliable results and improvements in operational efficiency.

The Xevo TQ Absolute XR is now officially available for orders, bringing cutting-edge mass spectrometry solutions to laboratories worldwide, enabling better efficiency, sustainability, and performance in analytical science.

Waters Corporation, with over 65 years of experience, is a global leader in analytical instruments, separation technologies, and software, serving diverse industries to ensure drug efficacy, food safety, and water purity. With more than 7,600 passionate employees in over 100 countries, Waters collaborates with customers in laboratories, manufacturing plants, and hospitals, propelling the benefits of pioneering science.

For more information, visit their product page. The Xevo brand, along with StepWave, ACQUITY, and waters_connect™, are trademarks of Waters Technologies Corporation.