DPX Technologies' Innovative Solutions Transform Genomic Testing with New Automated Workflows

DPX Technologies Pioneers Automated Solutions for Genomic Testing



In a significant advancement for the biotechnology sector, DPX Technologies has introduced new automated workflows and expanded compatibility features aimed at enhancing genomic testing methodologies. The company, renowned for its innovative solutions in automated sample preparation, is taking a leap forward with its latest offerings: MicroPorous Xtraction (MPX) Tips and NiXTips.

Revolutionizing Sample Preparation


Launched in 2024, NiXTips were originally designed for compatibility with Hamilton® Robotics platforms and Agilent Bravo systems. However, thanks to recent enhancements, they are now also applicable to the Integra VIAFLO semi-automated liquid handlers. This move opens avenues for laboratories seeking efficient alternatives to traditional, labor-intensive methods of genomic analysis.

The MPX Tips streamline the processes of nucleic acid extraction and cleanup, providing high-yield samples that serve as robust substitutes for conventional magnetic bead techniques, typically employed in next-generation sequencing (NGS) library preparation.

Addressing Common Challenges


Traditional methods often involve complex procedures that include bead capture time, carryover, and contamination risks. DPX Technologies' automation resolves these issues by significantly reducing manual handling and the likelihood of sample contamination or experimental inaccuracies. Utilizing a 1 mL MPX Tip for DNA extraction alongside NiXTips for size selection results in more efficient workflows, allowing laboratories to focus on analytical results rather than tedious preparation tasks.

We deeply appreciate the ongoing collaboration with our customers that has propelled the development of MPX technology and NiXTips beyond the beta-testing stage,” stated Dr. William Brewer, the Founder and CEO of DPX Technologies. “These innovations allow us to offer automated solutions that significantly improve genomic sample preparation.”

Advanced Features of the New Tips


The MPX Tips facilitate high-quality genomic DNA extraction from complex biological samples through an automated bind-wash-elute method. A notable feature of these tips is a needle support housing high-capacity microporous media, enhancing concentration factors during extraction and enabling replacements for less effective spin columns or magnetic bead workflows.

Similarly, NiXTips employ Solid Phase Reversible Immobilization (SPRI) methods, which allow for rapid and effective removal of unwanted components like primers and enzymes from PCR reactions, streamlining the cleanup process.

Customized Workflow Solutions


DPX Technologies stands out in its commitment to providing tailored method development and automation support, ensuring workflows are optimized to cater to unique laboratory variables such as sample volume, DNA sizes, buffer compositions, and binding cycles. This level of customization is crucial in achieving reliable and repeatable genomic testing results.

Moving Forward


As the field of biotechnology continues to evolve, innovations like those introduced by DPX Technologies are not only streamlining genomic testing but also paving the way for improved accuracy and efficiency in a variety of applications. The enhancements brought about by the integration of MPX Tips and NiXTips into laboratory workflows signify a pivotal step forward in automated genomic sample preparation.

For further insights into DPX's genomic solutions, adventurers can visit DPX Technologies.

DPX Technologies remains committed to its goal of unfurling the potential for scientists to tackle complex chemical and biological analysis challenges effectively. As such, ongoing collaborations with clients ensure that their products remain at the forefront of innovation within the biotech landscape.

Topics Consumer Technology)

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