#Japan #Tokyo #Space Seed Holdings #Regenesome #Global Knowledge Hub

Space Seed Holdings Showcases Innovations at Global Knowledge Hub Forum 2025

In August 2025, Space Seed Holdings, a leading deep-tech venture builder based in Tokyo, participated in the Global Knowledge Hub Forum (GKHF) held at The Legacy, NTU@one-north in Singapore. Under the leadership of President Kengo Suzuki, the company showcased its significant research and development roadmap focused on the intersection of fermentation and longevity, alongside updates on its strategic partnerships in the ASEAN region.

Insights into the Global Knowledge Hub Forum

The GKHF serves as a flagship innovation platform organized by Leave a Nest Singapore, aiming to foster collaboration among multinational corporations (MNCs), small and medium enterprises (SMEs), startups, researchers, and ecosystem builders. The event featured diverse programs, including thematic sessions, startup showcases, and one-on-one meetings between major corporations and selected startups. This provided an excellent platform for organizations like Space Seed Holdings to present their cutting-edge research.

Highlights from Space Seed Holdings’ Exhibition

At their booth, Space Seed Holdings utilized posters and interactive displays to present several key elements aligned with the mission of its subsidiary, Regenesome Inc. This mission aims to extend healthy lifespans and enhance human living environments, including potential lunar habitation by 2040. Regenesome focuses on aging control and regenerative medicine utilizing nanoparticles and exosomes.

Mission, Vision, and Value

• - Mission: To provide ground-adaptable anti-aging technologies needed for lunar habitation by 2040.
• - Vision: To validate aging control technologies that will extend healthy lifespans by 2030.
• - Value: Building knowledge in exosome science, networking in space science, and addressing health challenges on Earth and in space through robust R&D.

Research in Nanoparticle and Exosome Areas

The research highlighted at GKHF included advanced design strategies for microfluidic devices emphasizing the functional analysis of low-molecular-weight fractions containing a sake-derived nanoparticle known as “SAKESOME.” Their initiative also evaluated the interaction with targeted cells such as neural, muscle, and immune type cells and proposed engineering applications for assessing these interactions.

Evaluating Hypoxic Environments

The company reported on their studies focusing on “Aging Care Space,” which aims to understand aging care effects due to hypoxic environments. Their findings suggested that low oxygen levels can significantly influence cellular function and aging, presenting new avenues for potential applications.

Advancements in Fermentation-Driven Materials

Additionally, the team detailed their prototype creation activities involving sake lees, a byproduct of the fermentation process, transformed into high-performance materials through a method known as Spark Plasma Sintering (SPS). This work outlined foundational designs for high-pressure configurations and sintering processes, highlighting the application potential in high-tech spheres such as energy and electronics.

Fermentation and Longevity Fund Program

To accelerate R&D and business development from 2024 to 2026, Space Seed Holdings plans to implement a funding program dubbed the Fermentation and Longevity Fund. This initiative aims not only to target high-revenue domains but also to explore technologies that contribute to enhancing human living environments, including lunar habitation.

Embracing AI for Research and Development

Furthermore, they showcased their integration of generative AI in various stages from research visualization, issue extraction, and development planning to promotion efforts. The structured utilization of AI enables quicker and more efficient implementation in practical scenarios and international deployments, enhancing overall operational strategies.

Looking Ahead: Accelerating Open Innovation in ASEAN

Looking towards the future, Space Seed Holdings aims to foster collaborative research and business development across ASEAN. This includes engaging universities, research institutions, large corporations, and startups in small-scale joint investments and local project execution. Their ongoing efforts aim to leverage knowledge exchange in closed-system technologies for space, as well as tackle regional challenges through advanced aquaculture technology and bioengineering solutions. Plans are already underway for collaboration in Malaysia’s healthcare sector and industrial implementations in Indonesia, emphasizing a transformation from bottom-up prototyping to systematic design and scaling.

About Regenesome Inc.

Regenesome aims to provide new solutions in aging control and regenerative medicine using nanoparticles like exosomes. Through detailed analyses of exosomes produced by various cells and molecular biology-driven designs of nanoparticles, they explore their functions within biological systems. Their work seeks to advance medical technology applications and contribute to human space endeavor solutions while enhancing healthy lifespans.

Learn more about Regenesome

About Space Seed Holdings

Space Seed Holdings is a visionary deep-tech venture builder focused on research and business development across food, health, materials, and space-related domains. By leveraging capital and business alliances, promoting cross-border collaboration primarily within ASEAN, and utilizing generative AI for research visualization and implementation acceleration, the firm aims to facilitate the societal impact of technologies extending healthy lifespans and expanding human living environments.

Learn more about Space Seed Holdings