XtalPi Holdings Achieves Remarkable Growth with 2025 Interim Results

XtalPi Holdings Achieves Remarkable Growth with 2025 Interim Results



XtalPi Holdings Limited has announced its 2025 interim financial results, showcasing an extraordinary surge in revenue and profits. The company, a pioneer in integrating artificial intelligence (AI) and robotics for drug discovery, reported a 404% increase in revenue year over year, amounting to RMB 517 million for the first half of 2025. This remarkable growth is coupled with a landmark achievement as the company recorded its first-ever half-year profitability, with an adjusted net profit of RMB 141 million.

Key Highlights of the Financial Report


  • - Revenue Surge: USD 517 million achieved in the first half of 2025.
  • - Record Profitability: First half-year adjusted net profit of USD 141 million.
  • - Index Recognition: Inclusion in the MSCI China Small Cap Index underscores international capital markets' recognition of XtalPi's value.

Breakthroughs in Drug Discovery


XtalPi's Drug Discovery Solutions have seen tremendous growth, with revenues soaring 615.2% from RMB 60.85 million to RMB 435.2 million compared to H1 2024. This success can be attributed to major collaborations and successful project milestones. One notable partnership was signed with Professor Gregory Verdine, an eminent biopharmaceutical scientist. This collaboration includes an initial USD 51 million payment, enhancing XtalPi's global strategy and its AI-driven drug discovery capabilities.

Significant Collaborations and Achievements

1. Chronic Disease Program: Projects in collaboration with a leading biopharmaceutical company achieved key milestones ahead of schedule.
2. PRMT5 Inhibitor PE-0260: Development of a first-in-class inhibitor now progressed to IND application and clinical trials in partnership with PharmaEngine.
3. Prix Galien Award Nomination: A treatment for diffuse gastric cancer, developed with Signet Therapeutics, is nominated for the prestigious Prix Galien Award, marking a significant recognition for XtalPi.

Advancement through AI and Robotics


In the field of Intelligent Robotics Solutions, revenue grew by 95.9%, reaching RMB 81.9 million in H1 2025. XtalPi is pioneering a new era in chemistry with advanced AI models and robotic systems working synergistically to accelerate research and development. The company's unique integration of high-throughput data generation and AI models has led to improved success rates and efficiency in drug and new material development.

Innovations in Robotic Solutions

  • - NeoDispenser Technology: XtalPi’s next-generation robotic systems, featuring the NeoDispenser, streamline processes in chemical research with remarkable dexterity and efficacy.
  • - PatSight: An LLM-powered patent mining platform that improves data extraction accuracy for drug development.

Future Outlook


XtalPi is dedicated to revolutionizing scientific discovery through the combination of AI, embodied intelligence, and human insight. By tackling challenges in drug and materials discovery, the company aims to create transformative advancements in the field. Continuous improvements in their drug development solutions suggest an even brighter future as they expand their reach both domestically and internationally.

XtalPi Holdings Limited stands at the forefront of a new research paradigm, reshaping not just the landscape of pharmaceutical and materials science but also the very fabric of future human health and well-being. Through innovative strategies and groundbreaking technologies, XtalPi is poised to play a pivotal role in the evolution of drug discovery and development in the years to come.

Topics Business Technology)

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