#Singapore #National University Hospital #Yong Loo Lin School of Medicine #KK Women's and Children's Hospital

Singapore's Food Allergy Study: A Comprehensive Investigation

A collaborative effort by clinicians and researchers from the National University Hospital (NUH), Yong Loo Lin School of Medicine, and several key institutions marks a significant step in understanding food allergies among children in Singapore. This extensive four-year study, titled The Singapore Food Allergy Story, aims to analyze the growing prevalence of food allergies in the nation, targeting over 2,000 children.

The Growing Concern of Food Allergies

Food allergies are fast becoming a pressing health concern in Singapore, with increases in reported cases observed in pediatric clinics. Common allergens affecting young children include eggs, milk, and peanuts, while shellfish allergies are prevalent among older adolescents and young adults. In recent years, the number of food challenge sessions – a procedure aimed at diagnosing food allergies – has surged by 60% between 2022 and 2024, indicating heightened awareness and concern from parents.

Objectives of the Study

The main goals of The Singapore Food Allergy Story are:
1. Determine Prevalence: To gather current data on how many children are affected by food allergies in Singapore.
2. Impact Assessment: To evaluate how these allergies affect children's nutrition, growth, and mental health.
3. Inform Future Decisions: Provide insights that can lead to improved social support networks and educational materials for families affected by food allergies.

Structure of the Research

This pioneering study will be conducted in two phases over four years:

• - Phase One (started February 2025): Involves surveying parents and caregivers of children aged 12 to 24 months visiting polyclinics for routine check-ups. Approximately 2,000 families will be asked to fill out questionnaires to assess possible allergic reactions, with follow-ups at NUH or KKH for any positive reports.
• - Phase Two (commencing July 2025): Focuses on around 400 children aged 0-18 who have been diagnosed with allergies to milk, eggs, peanuts, or shellfish. This phase will offer deeper investigations including nutritional assessments and the collection of biological samples like blood and stool.

Collaboration with Support Groups

The research team is working closely with parent groups such as the Singapore Parents of Eczema and Allergy Kids (SPEAK), which emphasizes the importance of patient-relevant outcomes that directly address families' needs.

Expected Outcomes

Associate Professor Elizabeth Tham, the Lead Principal Investigator, expressed hope that the research will greatly enhance understanding of food allergies and their broader impacts, aiming to create safer environments for children to thrive. The study's insights are expected to inform guidelines for healthcare professionals, improving care quality and life for children battling food allergies.

This investigation is not just a scientific endeavor; it reflects a commitment to the well-being of Singapore's children, fostering healthier communities and offering necessary support to families who navigate the challenges posed by food allergies.

Conclusion

With support from the Ministry of Health and an array of institutions, this landmark study stands to transform how food allergies are perceived and managed within Singapore, paving the way for enhanced public health initiatives that could reshape the future experience of children dealing with allergies.