New Study Reveals MiniMed™ 780G Achieves Time-in-Range Goals Even With Missed Boluses

New Study Reveals MiniMed™ 780G Achieves Time-in-Range Goals



A recently published retrospective analysis in Diabetes Care has provided illuminating insights into the effectiveness of the MiniMed™ 780G insulin delivery system. This study specifically illustrates that users can attain the American Diabetes Association (ADA) recommended time-in-range (TIR) goals—even on days when they forget to administer their mealtime boluses. The findings signify a notable advancement in diabetes management solutions available to patients.

Key Findings of the Analysis



The research was conducted using real-world data sourced from Medtronic's CareLink™ platform, encompassing over 369,000 global users of the MiniMed™ 780G system. Among these users, a subset was identified who had experienced at least 10 days without administering boluses during their meals. A staggering 76.3% of users who utilized the system with recommended optimal settings achieved the TIR goals on days when boluses were missed—a significant metric considering the real-life challenges of diabetes management.

Dr. Jennifer McVean, Senior Medical Affairs Director for Medtronic Diabetes, and the lead investigator of the study, articulated the reality of missed boluses, noting, "While labeling requires meal bolusing for all automated insulin delivery systems, including the MiniMed™ 780G system, missed boluses are a reality in real-world use."

In addition to TIR goals, the study also measured other key glycemic outcomes. It revealed that individuals employing recommended settings had a mean sensor glucose level of 149 mg/dL, as opposed to 160 mg/dL in those using suboptimal settings. This variation underscores the potential benefits that come from harmonizing device settings with user behavior.

The Burden of Mealtime Management



Mealtime remains one of the most daunting aspects for individuals managing type 1 diabetes. The requirement to calculate insulin doses based on carbohydrate intake generates considerable stress—often described as diabetes distress. Research from 2024 indicated children and adolescents utilizing automated insulin delivery systems missed, on average, 2.2 boluses per day, with each missed bolus decreasing TIR by nearly 10%.

The MiniMed™ 780G's SmartGuard™ technology offers a beacon of hope. It operates by auto-adjusting insulin through algorithmic calculations every five minutes based on real-time sensor data, which helps to compensate for the occasional missed bolus or underestimated carbohydrate intake. Although using the device without announcing meals is not endorsed, the findings suggest that patients can still benefit significantly from its automated features to maintain glucose control.

Que Dallara, EVP and President of Medtronic Diabetes, expressed optimism about the potential of the MiniMed™ 780G system, stating, "These findings underscore the advanced capabilities of the MiniMed™ 780G system and its potential to ease the daily burden of diabetes care."

Conclusion



The recent study highlights a profound advancement in diabetes technology with Medtronic’s MiniMed™ 780G system. By demonstrating significant glycemic control even in instances when users forget to administer boluses, this device offers tremendous support for managing type 1 diabetes. It reinforces the value of tailored diabetes management tools that adapt to the unpredictable nature of daily life.

For those navigating the myriad challenges of diabetic care, the promise shown by the MiniMed™ 780G system can facilitate a smoother journey toward achieving desired health outcomes. The message is clear: even in imperfect conditions, there are solutions designed to help people thrive.

To learn more about the findings from this pivotal study, visit Medtronic Diabetes or consult with your healthcare provider about potential integrations into your diabetes management strategy.

Topics Health)

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