Exploring the Application of 3D In Vitro Models in Biomedical Research

Application of 3D In Vitro Models in Biomedical Research

On August 6, 2025, at 13:30, CMC Research will host a live webinar focusing on the application of 3D in vitro models using human normal oral mucosa for biomedical research. Led by Professor Kenji Izumi from Niigata University, this seminar is designed for researchers and healthcare professionals interested in oral mucosa studies, especially those involved in pharmaceutical and biotechnology sectors.

Webinar Details

- Date & Time: August 6, 2025, from 13:30 to 16:30 (JST)
- Registration Fees:

- General Admission: ¥29,700 (tax included)
- Newsletter Subscribers: ¥17,600 (tax included)
- Academic Rate: ¥17,600 (tax included)

- Platform: Zoom (details will be provided via email post-registration)

Through this seminar, participants will:

- Learn how to culture primary epithelial and fibroblast cells from oral mucosa.
- Discover methods to create a 3D cell culture comprising an epithelial layer and a stroma layer under gas-liquid phase conditions (Organotypic Culture).

Seminar Focus

In recent years, three-dimensional cell cultures, represented by organoids, have gained attention as methods that better replicate the in vivo environment compared to traditional two-dimensional cell cultures. This technique also serves as an alternative to animal testing. Professor Izumi will explain how these 3D cultures can enhance the precision and efficiency of research, especially concerning the complex structures and physiological conditions of human tissues.

The seminar will include:
1. Fundamental Principles of 3D Culture Technology and Its Advantages.
2. Methods for Culturing Primary Human Oral Mucosa Cells.
3. Construction of Normal Oral Mucosa 3D In Vitro Models and Their Production Methods.
4. Applications in Oral Cancer Research, covering aspects such as mimicking the tumor microenvironment and developing treatment methods.
5. Exploration of Future Research Tools relevant to oral mucosa studies and the development of treatments for oral cancers and diseases.

Using video demonstrations, Professor Izumi will show the practical steps to establish primary cultures of oral mucosal cells and how to create the 3D in vitro models derived from them. Ideas and examples from ongoing cancer research in his lab will also be shared. Following the presentations, participants will have the opportunity to engage in a Q&A session, fostering discussion among researchers and technicians.

About the Speaker

Professor Kenji Izumi is affiliated with Niigata University’s Graduate School of Medical and Dental Sciences. After graduating from Niigata University in 1988, he engaged in oral surgery, completing his doctoral studies in 1992. His academic journey includes research at the University of Michigan and his role as a Research Scientist/Clinical Assistant Professor there. He became an associate professor at Niigata University in 2009 and established CollaWind Co., Ltd. as CEO in 2023. Professor Izumi is a respected member of several academic societies, including the Japanese Society for Regenerative Medicine and the Japanese Society for Biomaterials.

Register today for insights into advanced research methodologies in oral mucosa studies and beyond! Visit CMC Research for more details and registration.

Note: Audio recording or video capturing during the session is strictly prohibited.