#Canada #Waterloo #High Q Technologies #protein research #EPR Measurement

High Q Technologies Launches EPR Sample Measurement Service

High Q Technologies, a leader in quantum-enabled Electron Paramagnetic Resonance (EPR) spectrometers, has unveiled a new service geared towards advancing research in structural biology. On September 16, 2025, the company announced the launch of the High Q Sample Measurement Service, designed specifically for both academic researchers and professionals in the pharmaceutical industry.

The revolutionary measurement service allows researchers to better understand the molecular dynamics and conformational probabilities present within their protein and macromolecule samples. By unlocking critical insights, this service promises to significantly enhance the structural models developed through sophisticated tools like AlphaFold and Cryo-EM. The Vice President of Operations at High Q, Don Carkner, underscored the crucial role of EPR spectroscopy in addressing some of the most challenging problems in structural biology. He highlighted that EPR is particularly well-suited for investigating intrinsically disordered proteins (IDPs), proteolysis-targeting chimera (PROTACs), and membrane-bound proteins.

Carkner stated, "There is a clear unmet need for EPR spectroscopy within the structural biology toolkit. The need for data that only EPR can provide has never been higher," emphasizing the technology's necessity as a screening tool for expensive Cryo-EM measurements or in conjunction with innovative AI approaches such as AlphaFold and RoseTTaFold.

With the introduction of this service, researchers now have the opportunity to send their samples to High Q where they will utilize their advanced FATHOM EPR systems. Each sample will receive a comprehensive report that includes detailed distance distribution and sample characterization, making the findings suitable for publication.

In light of recent budgetary constraints impacting research funding, particularly the year-over-year decline in NIH funding reported by the Association of American Medical Colleges, High Q's service comes as a timely solution. Director of Product Management, Rudra Maharajh, noted, "In the current funding environment, it is increasingly difficult to receive grants for large capital purchases. High Q's Sample Measurement Service offers a path forward for laboratories that either lack access to EPR or cannot secure funding for their equipment; scientific discovery need not be hindered."

Alongside the new service, High Q Technologies continues to market its cutting-edge FATHOM EPR system, which is set to commence receiving samples in the fourth quarter of 2025. More information about the new measurement service can be accessed through High Q's official website at highqtechnologies.com.

About High Q Technologies

High Q Technologies stands out as an innovative entity committed to developing quantum-enabled scientific instruments that excel in ultra-high sensitivity biophysical and chemical analysis. By leveraging modern microwave quantum optics techniques in EPR spectroscopy, the company is on a mission to redefine the standards in protein structure determination, innovate drug discovery, and foster the development of new therapeutics. The company is supported by leading investors such as Quantum Valley Investments and the co-founders of Blackberry, Mike Lazaridis and Doug Fregin, along with backing from the Government of Canada through the Federal Economic Development Agency for Southern Ontario (FedDev Ontario). High Q Technologies is headquartered in Waterloo, Ontario, Canada.