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Enhancing Skin Hydration: A Breakthrough by Daiichi Sankyo Healthcare

Daiichi Sankyo Healthcare, headquartered in Chuo-ku, Tokyo, has recently made a significant advancement in the skincare sector by developing a unique formulation designed to enhance the skin's moisture retention capacity. This innovation centers around a newly developed amino acid complex that was rigorously tested for its efficacy in boosting the hydration levels of sensitive skin.

Background of the Research

The company has dedicated many years to researching sensitive skin, emphasizing the need to understand and address the challenges faced by individuals with compromised skin barriers. The research initially highlighted that sensitive skin is more prone to dryness compared to healthy skin. Therefore, the study focused on the crucial role of bound water in the stratum corneum, as it is a key component determining the skin's ability to retain moisture.

Bound water plays a vital role by connecting with natural moisturizing factors in the skin, thus making it less prone to evaporation even in dry environments. The amino acid complex developed by Daiichi Sankyo has shown the potential to support the skin’s barrier function while providing essential hydration.

Research Methods and Findings

The company conducted a series of tests using human skin-derived stratum corneum sheets to evaluate how the new amino acid complex impacts bound water levels in the skin. To create a model of compromised barrier function, the sheets were treated with sodium dodecyl sulfate (SDS) to simulate sensitive skin conditions.

Testing Procedure

Dried stratum corneum sheets were treated with various formulations. By utilizing differential scanning calorimetry (DSC), researchers measured the amount of bound water in the treated sheets. Measurements were first taken from sheets treated with purified water (healthy skin model) and then compared with those treated with SDS (compromised barrier model). Subsequently, the impacts of applying the new amino acid complex formulation to the compromised sheets were analyzed.

Results of Testing

In the compromised barrier model, it was found that the amount of bound water was significantly lower compared to the healthy skin model treated with purified water. Furthermore, applying the new amino acid complex formulation to the compromised sheets resulted in a statistically significant increase in the bound water levels within those sheets.

Moreover, when glycerin - a widely recognized moisturizing agent - was added to the new amino acid complex formulation, there was a notable increase in bound water levels compared to when the amino acid complex was used alone. This suggests that combining glycerin with the new amino acid complex could lead to an even more effective moisturizing product.

Future Perspectives

The research findings confirm that the new amino acid complex can amplify the levels of bound water in the stratum corneum. When combined with glycerin, it further enhances this effect, indicating a promising potential for developing products aimed at improving moisture retention in those with sensitive skin. Daiichi Sankyo Healthcare plans to apply this innovative research to their product development strategies, focusing on addressing the concerns of sensitive skin and ultimately enhancing the quality of life for consumers.

About Daiichi Sankyo Healthcare

As a part of the Daiichi Sankyo Group, Daiichi Sankyo Healthcare operates under the philosophy of providing pharmaceuticals that cater to diverse healthcare needs. The company not only focuses on OTC pharmaceuticals but is also expanding into functional skincare, oral care, and dietary supplements, aiming to become a partner in creating healthier lifestyles. Through these initiatives, Daiichi Sankyo Healthcare promotes self-care, striving for a healthier and more beautiful society.

References

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