#Clinical Trials #healthcare provider #Patient Advocate Foundation

Significant Gap Between PCP Support for Clinical Trials and Patient Participation

A recent national survey conducted by the Patient Advocate Foundation sheds light on a troubling inconsistency within the healthcare system—while primary care providers (PCPs) express strong support for clinical trials, patient access and participation remain surprisingly low. The research highlights the challenges that stem from an information gap and workflow issues affecting conversations around clinical trials in everyday medical care.

Overview of the Survey

The survey, conducted by The Harris Poll, interviewed 503 actively practicing, board-certified PCPs across the United States between March 5 and 18, 2026. With impressive results showing 98% of PCPs viewing clinical trials positively and 96% believing in their value to the medical community, one would expect a more proactive approach to discussions about clinical trials with patients. However, the data reveals otherwise—only 37% of PCPs reported ever having referred a patient to a clinical trial, despite 86% saying they are likely to do so.

Many PCPs admit that they only bring up clinical trials when prompted by their patients, with 42% stating they wait for patients to mention it, and 12% claiming they never discuss it. These figures indicate a critical disconnect between the PCPs' acknowledgment of the trials' significance and their implementation in practice.

The Patient Perspective

Further, a patient poll conducted in 2026 found that nearly two-thirds of adults with chronic health conditions reported that their healthcare providers had never explained the option of participating in clinical trials. Yet, 71% stated they would consider participation if offered the opportunity. It seems there is a willingness among patients to engage in clinical trials if only they could receive more straightforward, thorough information and encouragement from their healthcare providers.

The recurring themes among patients reveal key factors that could bridge this gap in participation. Respondents pointed to the need for compensation for their time and expense (52%), clear information on risks and benefits (46%), and a recommendation from their healthcare provider (43%). However, barriers remain—many noted logistical issues such as travel distances to trial sites and the financial burdens associated with participation.

Factors Influencing Provider-Patient Conversations

PCPs also noted various challenges that prevent effective clinical trial discussions. Limited awareness of available trials is a significant issue, with 14% of providers not regularly receiving relevant information and 51% relying on colleagues rather than structured resources. Operational difficulties, including administrative burdens and lack of prioritization for clinical trials in practice, further complicate their role in facilitating patient engagement.

Bridging the Gap

To address these concerns, the Patient Advocate Foundation's