#Canada #Waterloo #High Q Technologies #FATHOM EPR #Protein Dynamics

High Q Technologies Introduces FATHOM™ EPR Spectrometer

On January 7, 2025, High Q Technologies announced the commercial launch of its latest innovation: the FATHOM™ EPR spectrometer. This advanced spectrometer is designed to facilitate automated measurements of dipolar distance distributions, providing crucial insights into the conformations and dynamics of proteins.

Innovative Design for Enhanced Research

The FATHOM EPR spectrometer stands out in its class by featuring a 5 sample cartridge that enables users to conduct multiple tests simultaneously. This groundbreaking system automates calibration, measurement, and analysis, allowing researchers to operate it with just a push of a button and walk away to focus on their biochemistry instead of manual adjustments.

Rudra Maharajh, the Director of Product Management at High Q Technologies, expressed excitement over the first commercial sale of the FATHOM system to a consortium led by Professor Reza Dastvan. The consortium specializes in studying various health issues, including neoplastic, cardiovascular, and neurodegenerative diseases at Saint Louis University School of Medicine. Maharajh believes that the FATHOM EPR will significantly boost their research capabilities in human health.

Enabling Advanced Research

The acquisition is hailed not only as a significant step for High Q Technologies but also as a pivotal moment for Professor Dastvan's lab. He commented, “We eagerly anticipate utilizing this compact, fully automated spectrometer. In this era of Cryo-EM and AI, it is truly a game-changing advancement for the field of EPR/DEER spectroscopy.” This sentiment highlights the potential influence the FATHOM system may have on ongoing research methodologies and outcomes in the biophysical analysis of proteins.

Key Features of FATHOM EPR Spectrometer

The FATHOM spectrometer is equipped with several vital features that enhance its usability and efficiency:

• - Automated Calibration and Analysis: The spectrometer can process up to five samples simultaneously, streamlining workflow in research laboratories.
• - Reduced Sample Volume: It requires over ten times less sample volume compared to other commercial EPR systems, making it both practical and economical for research purposes.
• - Cryogen-Free Operation: This fully integrated system eliminates the need for cryogens, simplifying the operational logistics and expenses associated with traditional spectrometers.

High Q Technologies aims to revolutionize the landscape of protein structure determination and significantly impact the fields of drug discovery and therapeutic development. By implementing cutting-edge quantum optics techniques into EPR spectroscopy, the company redefines analytical standards in the scientific community.

About High Q Technologies

High Q Technologies is recognized for its commitment to pushing the boundaries of scientific research through the development of quantum-enabled instruments. Their innovative technologies cater to ultra-high sensitivity biophysical and chemical analysis. Interested parties can learn more about High Q Technologies and the capabilities of the FATHOM spectrometer by visiting highqtechnologies.com.

The FATHOM EPR spectrometer promises to change the course of research in structural biology, ultimately leading to advancements in medical science and treatment solutions for complex diseases. With its commercial release, High Q Technologies is poised to leave a significant mark on the field of biophysical research.