a2z Radiology AI Secures $4.5M Seed Funding to Enhance CT Imaging Solutions

a2z Radiology AI Secures $4.5 Million Seed Round

In an impressive move to accelerate its growth, a2z Radiology AI has announced a successful seed funding round of $4.5 million. This funding, led by prominent investors Khosla Ventures and SeaX Ventures, aims to support the company in scaling its innovative solutions for medical imaging interpretation. Aiming to revolutionize the field of radiology, a2z is on the path to deploying its FDA-cleared triage system commercially and expanding its research and development efforts for a broader array of imaging interpretation capabilities.

This investment comes after a significant milestone in the healthcare technology space: receiving FDA clearance for their advanced system, a2z-Unified-Triage. This groundbreaking tool notably triages seven urgent conditions identified in abdomen-pelvis CT scans—a first for the U.S. market. The company showcased its innovative technology at the RSNA 2025 conference, presenting the first prospective study that assessed AI-assisted preliminary report drafting for abdomen-pelvis CT scans.

The findings from this study were promising; AI assistance resulted in a 17.8% reduction in reporting time, a 14.8% increase in radiologist confidence, and a 22.4% decrease in mental strain experienced by radiologists. Additionally, the study confirmed that the implementation of AI could enhance the detection of critical findings without increasing the rate of false positives. These early results provide compelling evidence that comprehensive AI has substantial potential in improving both accuracy and efficiency in radiology—a sector that has oftentimes been challenged regarding the real-world effectiveness of AI applications.

Vinod Khosla, a prominent figure from Khosla Ventures, emphasized the transformative capacity of AI in radiology, stating, "Radiology is one of the areas that will benefit the most from AI, ensuring no disease goes undetected. While others may focus on single conditions, a2z uniquely has the capability to evaluate imaging for a wide range of issues, moving closer to the comprehensive skill set of a practicing radiologist."

Dr. Kid Parchariyanon, the Founder and Managing Partner of SeaX Ventures, articulated that the timely response to urgent health concerns often hinges on radiological assessments, which can be delayed due to an overwhelmed workforce. He praised a2z for addressing this critical gap with technology that offers expert-level insights directly to clinicians at the point of care, highlighting the need for advancements that can positively affect patient outcomes.

As the demand for imaging services continues to surge—particularly with over 20 million abdomen-pelvis CT examinations conducted annually in the U.S.—health systems are increasingly pressured by workforce shortages. a2z's strategic approach differs from conventional AI solutions that only target singular conditions; the company aims to enhance the way AI evaluates images comprehensively, in line with radiologists' actual workflows.

Pranav Rajpurkar, a co-founder of a2z Radiology AI and an Associate Professor at Harvard Medical School, noted that the feedback received at RSNA affirmed the importance of their work: "We are creating AI that considers every detail from A to Z in each scan. This funding is vital as we continue to invest in R&D while advancing our cleared technology to the healthcare teams that need it."

CEO and co-founder Samir Rajpurkar expressed enthusiasm about the upcoming developments, stating, "We are pioneering comprehensive interpretation of complex imaging studies at a level that has not been achieved before. This funding will not only facilitate partnerships with health systems but will also propel product development and commercial rollout slated for 2026."

With a mission to enhance the accessibility of radiologist-level interpretations on demand, a2z Radiology AI stands at the forefront of integrating AI into medical imaging. Founded in 2024, the company brings together expertise from the fields of medicine and technology to build solutions that provide immediate insights into CT scans, beginning with in-depth abdomen-pelvis analyses and aspiring to expand across various imaging modalities.

In conclusion, the backing from Khosla Ventures and SeaX Ventures is a significant step forward for a2z Radiology AI as it strives to meet the evolving demands in radiology, offering reliable and efficient AI-driven solutions that have the potential to change patient care for the better.