Sake Nanoparticles
2025-12-26 00:22:05

Innovative Patent for Immune Cell Activation Using Sake-Derived Nanoparticles

Innovative Patent for Immune Cell Activation Using Sake-Derived Nanoparticles



In a groundbreaking achievement, Regeneromes Inc., a key company within Space Seed Holdings, has announced a joint patent application with Tokyo Science University. This patent pertains to an "immune cell activator and method to activate immune cells" based on research conducted with Professor Takahiro Adachi at the university's International Institute for Medical Engineering and Innovation.

Discovering the Power of Sake



The study has uncovered the presence of new functionalities within nanoparticles derived from sake, specifically focusing on the activation of immune cells, particularly B cells and T cells. These nanoparticles are not only purifiable through standard filtration techniques but are also comprised of complexes from sugars and proteins produced by yeast and koji mold. The study confirmed that these nanoparticles range from 1 to 500 nm in size, showcasing their unique structural properties.

Experimental Insights and Applications



Utilizing Flow Cytometry (FCM), the research outlines a detailed experimental process illustrating the nanoparticles' effectiveness in activating immune cells. This discovery offers the potential for new immune-regulating materials that could have significant applications in regenerative medicine and immune maintenance technologies.

Background and Significance of the Research



Regeneromes has been at the forefront of advancing extracellular vesicle-based longevity science and space medicine. The "sake-derived nanoparticles" featured in this research are thought to be generated through the unique fermentation processes intrinsic to sake brewing, which allows for the formation of these distinctive nanoparticle assemblies.

Future Developments



Building on these promising findings, Regeneromes aims to leverage the immune-regulating functionalities of these nanoparticles to develop healthcare products. Additionally, the company seeks to collaborate with the sake industry to enhance the value of local fermentation resources. The patent application signifies a crossroads between traditional fermentation culture and contemporary biotechnology, holding great promise for human health maintenance.

About Regeneromes Inc.



Regeneromes is committed to providing innovative solutions for aging prevention and regenerative medicine using nanoparticles such as exosomes. By May 2025, they intend to establish their headquarters and research facility, the "Takanawa Longevity Lab," to accelerate business development and research efforts. The ultimate goal is to contribute to extending human health spans while simultaneously aiding humanity’s ventures into space through the development of advanced medical technologies and solutions in the field of space medicine.

For more details, visit: Regeneromes Official Website

About Space Seed Holdings Inc.



Space Seed Holdings operates under the mission of turning science fiction into non-fiction. As a deep tech venture builder in the space sector, it engages in investment, research, and business creation. The company actively supports initiatives that implement fermentation and longevity technologies in society, notably through its "Fermentation and Longevity Fund" program. Their objective is to gather the necessary technologies for human habitation in space by 2040 in collaboration with various stakeholders.

For more information, explore: Space Seed Holdings Official Website


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