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Optimized Conjugation Solution for Precise Extrahepatic Delivery of Small Nucleic Acid Drugs

Small nucleic acid drugs, including siRNA and antisense oligonucleotides (ASOs), have revolutionized therapeutic strategies by targeting diseases at the genetic level. However, delivering these agents effectively to the intended sites in the body remains a significant challenge due to issues related to stability, cellular uptake, and potential toxicity. To address these hurdles, Xtalks is hosting a free, informative webinar focused on the latest conjugation methods and their applications in improving the delivery of small nucleic acid drugs.

Webinar Overview

Scheduled for October 28, 2025, at 2 PM EDT, this webinar will feature Jacob Guo, PhD, the Director of the Nucleic Acid Platform at GenScript Biotech Corporation. Attendees will explore key topics about conjugation strategies that enhance drug delivery and therapeutic efficacy. The event promises to provide invaluable insights into how these methods represent a significant advancement in the field of nucleic acids.

Key Topics to Be Covered

1. Advances in Small Nucleic Acid Drug Delivery
- Understand new methodologies that enhance the delivery process of small nucleic acid drugs.

2. Ligand-Mediated Extrahepatic Delivery Techniques
- Discover how different ligands can mediate the delivery of drugs outside of the liver, targeting specific tissues and cells effectively.

3. Advantages of DAR 1 Antibody-siRNA Conjugate
- Gain insight into the DAR 1 conjugate strategy that improves the silencing efficiency of siRNAs while ensuring stability against degradation.

4. Conjugation Solutions for Accelerating Precise Targeted Delivery
- Learn about innovative conjugation solutions that guarantee high-purity products capable of precise drug delivery with enhanced efficacy.

Significance of Targeted Delivery

Targeted delivery of small nucleic acids is pivotal in maximizing their safety and effectiveness. Conjugation with targeting molecules, such as antibodies or peptides, can substantially improve cellular uptake and bioavailability. Moreover, these strategies can mitigate potential immunogenicity and toxicity often associated with systemic administration.

Register Today

Don’t miss the chance to deepen your understanding of these advanced therapeutic strategies. Register for the webinar today to learn how cutting-edge conjugation techniques are shaping the future of small nucleic acid drug delivery.

For further details and to secure your spot, visit Xtalks' official page where you can find additional information about the featured speaker and topics.

About Xtalks

Xtalks, powered by Honeycomb Worldwide Inc., is a premier provider of educational webinars and digital content tailored for the global life sciences, food, healthcare, and medical device industries. With thousands of industry practitioners relying on Xtalks for quality content annually, webinars serve to keep them updated on critical developments and challenges in their fields.

For media inquiries regarding this event or information about hosting a webinar, please contact Vera Kovacevic at +1 (416) 977-6555 x371 or via email at [email protected].