#USA #Boston #Volta Labs #Callisto #Twist Bioscience

Automated Hybridization Capture by Volta Labs

Volta Labs, a leading innovator in sample preparation solutions for next-generation sequencing (NGS), has announced the launch of its automated hybridization capture application for the Twist Standard Hybridization v2 kit on the Callisto platform. This new tool, created in collaboration with Twist Bioscience, integrates cutting-edge hybridization capture chemistry with Volta's fully automated Callisto system, thus enabling researchers and clinical laboratories to achieve highly consistent enrichment performance within a streamlined process.

Streamlining the Hybridization Process

Udayan Umapathi, CEO of Volta Labs, emphasized that the integration of Twist's proven v2 kit with the unique architecture of Callisto results in precise temperature-controlled automation for hybrid capture. This enhancement simplifies workflows while ensuring uniform and reliable results accessible to all laboratories. Traditional hybridization methods often involved extensive manual labor and necessitated specialized technician expertise; however, with the new Callisto platform, hybrids' capture is transformed into an entirely automated, reliable process.

Benefits of Callisto

The hybridization capture technique is vital for targeted sequencing applications, especially when utilizing large panels or aiming to identify novel variants. Callisto streamlines this critical step by automating it. The platform's unique design facilitates precise manipulation of magnetic beads while maintaining uninterrupted and uniform temperature control throughout the hybridization capture process. This guarantees consistent enrichment performance, alleviating the variability often seen with manual or semi-automated approaches. Consequently, laboratories can expect reduced sequencing costs alongside improved coverage across a diverse array of panels.

Advantages of the Twist Standard Hybridization v2 Kit

Leveraging its silicon-based platform, Twist is capable of synthesizing DNA at scale, allowing for the creation of highly uniform NGS tools. The Standard Hybridization v2 kit from Twist provides researchers with high sensitivity and uniform coverage of their regions of interest. Emily M. Leproust, CEO and co-founder of Twist Bioscience, reiterated that their NGS tools are designed to expedite research cycles while reducing downstream sequencing costs. The synergy between the Twist Standard Hybridization v2 kit and Callisto empowers clients to achieve exceptional performance and efficiency within their workflows.

For more information, you can visit the Twist Hybrid Capture application page.

About Volta Labs

Volta Labs is a genomics application company dedicated to maximizing performance and scalability in genomic sample preparation through a state-of-the-art digital fluidic platform. The company aims to deliver unparalleled consistency in their solutions. For additional details about their products and services, visit their official website at www.voltalabs.com.