#USA #Boston #Ginkgo Bioworks #Volta Labs #Callisto

Ginkgo Bioworks Enhances Automation with Callisto

In an exciting development for the genomics industry, Ginkgo Bioworks has announced its collaboration with Volta Labs, a leading force in genomics applications. This partnership brings the Callisto Sample Prep System into Ginkgo's high-throughput laboratory, specifically targeting the automation of Next Generation Sequencing (NGS) processes that had previously posed challenges.

Revolutionizing Sample Preparation

Ginkgo Bioworks, known for its innovative approaches in cell programming and biosecurity, has identified key areas within its Illumina sequencing workflow that can significantly benefit from the capabilities of the Callisto system. The integration aims to improve the labor-intensive tasks associated with sample preparation, particularly those that are difficult to automate. Aimable Habimana, a Senior NGS Scientist at Ginkgo, emphasized the importance of automating functions such as PacBio library preparation and complex size selection processes, which are crucial for efficient sequencing.

“I appreciate the simplicity and efficiency that Callisto brings, particularly with its App Store concept. It not only helps in keeping our operating costs minimal but also allows us to utilize various sequencing technologies seamlessly,” remarked Alex Plocik, Senior Director of Genomics at Ginkgo Bioworks. This flexibility is essential for Ginkgo, which frequently manages thousands of samples that require careful pooling and clean-up across varying batch sizes.

The Advanced Features of Callisto

The Callisto system’s features, including advanced electrowetting, magnetic capabilities, and acoustic functionalities, enhance the precision of liquid separation and the elution of DNA from beads, making it suitable for high-throughput environments. Moreover, the proprietary VoltaNode technology adds a layer of flexibility that helps accommodate batch-level processing. For labs working primarily with short-read sequencing technologies, the Callisto’s latest app for double-sided size selection has become a significant tool for purifying and optimizing DNA fragments before sequencing.

Udayan Umapathi, founder and CEO of Volta Labs, expressed enthusiasm about the integration. “Ginkgo has been a pivotal partner since we started, and their insights were crucial in developing our solutions for high-throughput labs. I am eager to see the benefits that the Callisto system will bring to their Illumina workflows,” he stated.

A Partnership Rooted in Innovation

Both companies are dedicated to reshaping the landscape of biological research. Ginkgo Bioworks is recognized for its unique position as a platform for cell programming that delivers end-to-end solutions across various sectors including food, agriculture, and pharmaceuticals. Their commitment extends to biosecurity, where they are developing advanced technologies to address biological threats.

With the successful integration of Callisto, Ginkgo aims not only to enhance the efficiency of its genomic sequencing processes but also to continue driving innovation within the industry. As Volta Labs prepares to launch kits for the Double-Sided Size Selection app, Ginkgo stands at the forefront of these advancements, ready to push the boundaries of what's possible in genomic research.

For those interested in learning more about Ginkgo Bioworks or Volta Labs, details can be found on their respective websites where they share insights, updates, and innovative research outputs that reflect their dedication to advancing genomics.

In conclusion, this collaboration exemplifies how targeted technological advancements can streamline complex lab processes, ushering in a new era of efficiency in the field of genomics. As Ginkgo Bioworks continues to explore and expand its capabilities, the integration of the Callisto system marks a significant step forward in enhancing the scalability and consistency of genomic research.