#Japan #Tokyo #Microfluidics #Shibaura Institute #Regenesome

Regenesome Ventures into Neural Cell Research with Shibaura Institute

Regenesome Inc., a Tokyo-based startup dedicated to the research and development of aging control technology, has recently formalized a collaborative research agreement with the Biological Microfluidics Laboratory at Shibaura Institute of Technology. This partnership aims to advance the understanding of neural cell growth in a controlled microgravity environment using a 3D clinostat equipped with a microfluidic cell culture system developed by Shibaura University.

Objectives of the Collaboration

The primary goal of this research is to cultivate neural cells over a prolonged period on the 3D clinostat while measuring the growth of their axons, hence analyzing the effects of simulated microgravity on these cells. This study recognizes the significant stresses imposed by space environments on the human body, particularly concerning neural cell degeneration and aging.

Strengths of Shibaura Institute's Laboratory

The Biological Microfluidics Laboratory at Shibaura Institute of Technology, led by Professor Nobuyuki Funai, is renowned for its expertise in microfluidic technology and long-term cell culture. Their initiative aims to ‘‘contribute to life sciences through integrated microfluidic and cellular cultivation techniques.’’ The laboratory stands out for its:

• - Development of microfluidic devices that enable advanced cell cultivation on a single chip.
• - Precision-controlled perfusion culture systems capable of maintaining exact fluid dynamics parameters.
• - Unique designs for surrounding mechatronics structures that allow for long-term cell cultivation.
• - Proven experience in technologies that simulate space environments, such as microgravity perfusion culture systems.

The laboratory actively tackles cutting-edge challenges such as on-chip 3D capillary long-term culture and microgravity-simulated perfusion systems, all while contributing to the design and prototype development of the 3D clinostat for this collaboration.

Future Developments

This collaborative effort holds promise for producing insights that could extend healthspan both on Earth and in challenging environments like outer space. By utilizing Shibaura Institute's cutting-edge microfluidic technology, the research targets the innovative realm of aging and neuroscience. Discoveries from this joint study aim to build a technological foundation adaptable to extreme conditions, enhancing our understanding of how microgravity affects human biology.

About Regenesome Inc.

Regenesome is dedicated to delivering new solutions that combat aging and support regenerative medicine through the use of nanoparticles such as exosomes. The company emphasizes the importance of detailed analysis of exosomes produced by various tissues while molecularly designing nanoparticles to uncover their functional mechanisms. Through this, Regenesome strives to develop novel medical technologies utilizing nanoparticles, contributing to extended human healthspan and supporting humanity’s aspirations for space exploration.
Visit Regenesome’s website

About Space Seed Holdings

Space Seed Holdings, headquartered in Minato-ku, Tokyo, is committed to turning science fiction into reality through investment, research, and business creation. Their mission includes supporting the social implementation of fermentation and longevity technologies, exemplified by their ‘Fermentation and Longevity Fund’ program. With a vision for 2040, they aim to equip humanity with the essential technologies needed for life in space.
Learn more about Space Seed Holdings