Expert Panel Affirms Image-Guided Radiation Therapy is Safe and Effective for Nonmelanoma Skin Cancer

Overview of IGSRT



A panel of experts from the Dermatology Association of Radiation Therapy (DART) has confirmed the safety and effectiveness of Image-Guided Superficial Radiation Therapy (IGSRT) in treating nonmelanoma skin cancer (NMSC). Published in the January 2025 issue of SKIN The Journal of Cutaneous Medicine, the report underscores that IGSRT can often lead to outstanding cosmetic outcomes. This innovative approach is especially significant for patients who are hesitant about surgical options.

Background of the Study



DART, a national non-profit organization, is dedicated to raising awareness about radiation therapy in dermatology. The expert panel conducted an extensive review of available literature on IGSRT. Their rigorous analysis led to the establishment of ten consensus statements regarding its application in the treatment of NMSC, indicating a strong recommendation for its use in appropriate cases.

Key Findings of the Expert Panel


The panel, comprised of six board-certified dermatologists, employed a modified Delphi process to collaborate on their findings. Here are some critical insights from the report:
1. Effectiveness of IGSRT: The panel unanimously agreed (6/6) that IGSRT is a safe and effective treatment option for NMSC with a high cure rate.
2. First-line Treatment: IGSRT may be considered a first-line treatment for selected NMSC cases, with the recommendation based on SORT criteria.
3. Role of Dermatologists: Dermatologists are deemed the most suitable professionals to oversee and administer IGSRT treatments.
4. Cosmetic Outcomes: The therapy has shown to result in favorable cosmetic outcomes, making it an attractive option for patients focused on preserving the aesthetic appearance of their skin.
5. Patient Involvement: The panel emphasized that patients should be well-informed about all treatment options and included in the decision-making process regarding their care.

Implications for Patient Care


NMSC is a prevalent form of cancer, with over 5.4 million cases diagnosed annually in the United States. Traditional management methods such as surgical excision are common; however, IGSRT presents a non-invasive alternative that may be more appealing to some patients, especially those eligible for surgery based on various factors like age or overall health.

By utilizing high-resolution dermal ultrasound (HRDUS) together with radiation therapy, providers can visualize tumors effectively throughout the treatment process. This integration allows for enhanced precision and real-time adjustments during treatment, potentially improving overall outcomes for patients.

Expert Commentary


Dr. Deborah Sarnoff, a panel member and president of The Skin Cancer Foundation, stated that the evaluation of IGSRT reflects a commitment to patient empowerment concerning prevention and treatment options for skin cancer. Furthermore, DART Chairman Jacob Scott commended the panel for clarifying when IGSRT would be optimal and when alternatives would be necessary, reinforcing the importance of personalized care in dermatological practices.

Conclusion


The comprehensive consensus from the DART panel on IGSRT allows for a promising alternative in the treatment landscape of nonmelanoma skin cancer. As more dermatologists adopt this approach, it could revolutionize patient care by providing effective options that prioritize the well-being and preferences of individuals seeking treatment for skin cancer.

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