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10x Genomics Showcases Cutting-Edge Innovations at AGBT Meeting

At the recent Advances in Genome Biology and Technology (AGBT) General Meeting, 10x Genomics, Inc. (Nasdaq: TXG) announced a comprehensive roadmap of innovations aimed at revolutionizing single-cell and spatial analysis. The company's presence at this esteemed gathering highlights its commitment to advancing research capabilities and solidifying its position as a leader in high-performance single-cell research.

Major Highlights from the Meeting

Ben Hindson, Co-Founder and Chief Scientific Officer of 10x Genomics, underscored the company’s dedication to pushing the limits of what is achievable in the field of single-cell and spatial biology. According to Hindson, "After a record year of innovation, we continue to push the boundaries of what's possible in single cell and spatial biology, taking on the hardest challenges so researchers can make the biggest impact."

The innovations announced during AGBT aimed at enhancing the efficiency and usability of large-scale single-cell analysis. Key advancements include:

1. Plate-Based Workflows for GEM-X Flex

10x Genomics plans to implement plate-based workflows designed for their GEM-X Flex system. This innovation significantly increases the number of samples that can be processed in a single run, aiming for 700 samples per run with the impressive capability of recovering around 1 million cells from one lane and up to 8 million cells per chip. This new workflow promises high sensitivity and excellent sequencing efficiency, thereby transforming how researchers can design and scale their studies.

2. 10x Cloud Analysis for Large Studies

In an era where data management is crucial, the introduction of a new batch analysis feature will allow researchers to run hundreds or even thousands of analyses simultaneously. The 10x Cloud Analysis is designed to streamline data processing, enabling automation while leveraging 10x's robust infrastructure, further empowering researchers in handling large datasets.

Continued Innovation in Spatial Biology

10x Genomics is not only leading the charge in single-cell research; it is also expanding its technology leadership in spatial biology. The Visium platform has seen groundbreaking advances with the introduction of the Visium HD product, which enhances resolution significantly and is now compatible with FFPE, Fresh Frozen, and Fixed Frozen tissues.

Upcoming features for the Visium HD platform are set to include:

• - Visium HD 3': This assay promises to merge high resolution with superior workflow, allowing comprehensive analysis across various applications.
• - Visium HD Cell Segmentation: This technology will connect transcript data with cellular morphology, providing a clearer understanding of tissue organization and cellular interactions.
• - Visium HD XL: With an expanded capture area, this will facilitate deeper spatial gene expression analyses, further aiding biological discoveries.

Innovations in the Xenium Platform

The Xenium platform is also set to benefit from advancements that allow simultaneous measurement of RNA and protein on the same sample. This integration is designed to provide comprehensive insights into cellular functionality, enhancing the quality and efficiency of data obtained from such analyses.

10x Genomics plans to roll out a validated protein immunology panel that can cover up to 28 protein targets while utilizing their curated RNA panels, maximizing the data quality researchers can extract from single experiments.

Engaging Researchers Through Workshops and Presentations

During the AGBT event, 10x Genomics will host insightful workshops and presentations to demonstrate how these innovations can fuel biological discoveries. A notable workshop scheduled for February 23 promises live presentations on the research capabilities afforded by these new technologies, emphasizing the company's drive to keep researchers informed and engaged.

In summary, the roadmap unveiled by 10x Genomics at the AGBT Meeting encapsulates a strategic vision for the future of single-cell and spatial biology research. As the company prepares to enhance its product offerings, users can anticipate more efficient tools to tackle complex biological questions, ultimately pushing the frontiers of science and health forward. For more updates and detailed insights, you can connect with 10x Genomics via their website or social media channels.