#USA #Cambridge #TriNetX #August Calhoun #Jeff Margolis

TriNetX Appoints August Calhoun as New CEO

On July 27, 2026, TriNetX, known as "The Global Truth Engine for Better Human Health™," officially named August Calhoun as its new Chief Executive Officer. This decision marks a significant shift within the company's leadership mindset, as Jeff Margolis, who served as interim CEO since December 2024, transitions back to his role as Chairman of the Board.

Calhoun brings over 25 years of expertise in health technology and services, having honed his skills in various executive positions, and worked with leading organizations such as RLDatix, Optum Insight, Change Healthcare, and Siemens. His extensive background covers operations, sales, account management, and strategic planning, making him a prime candidate to lead TriNetX during its next phase of growth.

In his statement regarding the appointment, Calhoun expressed pride in his new role, emphasizing TriNetX's unique position in the global health arena. Over the past thirteen years, the company has built a trusted network of health data utilized by prominent health systems and life sciences firms to tackle their most complex research queries. The global reach and unmatched data quality of TriNetX place it in an optimal position to expand its influence in the market, further enhance its data resources, and provide actionable insights across the healthcare landscape.

Jeff Margolis lauded Calhoun’s appointment, noting that his experience in developing high-performing organizations in health technology and his deep understanding of data analytics and services perfectly align with TriNetX’s mission and growth aspirations. Margolis highlighted the achievements made during his transitional leadership, which included strategic collaborations and investments, notably with Regeneron, and enhancing the company's network, which now encompasses over 300 million patient records.

Moreover, Joe Bress, Carlyle's partner and global co-leader in Health, commented on Calhoun's appointment, expressing excitement about the strategic vision he brings to TriNetX as well as gratitude towards Jeff Margolis for navigate the organization through pivotal growth phases.

TriNetX's global network now aggregates clinical practice data from more than 300 million patients across 25 countries, thereby supporting clinical research, trial designs, and providing real-world data for life sciences companies, healthcare providers, and academic researchers worldwide.

As the company embarks on this new chapter under Calhoun's leadership, it remains committed to utilizing complex health data effectively to enhance healthcare outcomes worldwide. For more information, visit TriNetX's website and follow their progress on LinkedIn.