TriNetX LIVE™ Network Reaches Over 300 Million Patients, Enhancing Global Healthcare Evidence Base

TriNetX LIVE™ Network Reaches New Milestone



TriNetX, a global leader in federated health data networks, recently announced that its TriNetX LIVE™ network has officially surpassed the threshold of 300 million patients. This remarkable milestone reflects the accelerated international growth of the network, which provides pharmaceutical companies, academic researchers, healthcare providers, and health tech innovators with access to reliable, up-to-date, clinically relevant, and globally representative data derived from real-world practices.

In the past, real-world data (RWD) faced a significant challenge due to fragmentation. Research teams focusing on drug discovery relied on one source, while those involved in study planning utilized another, and teams responsible for post-market safety monitoring turned to yet another. This separate use of data led to inefficiencies, prolonging decision-making processes and introducing inconsistencies. TriNetX's single, harmonized network now supports every phase of research – from hypothesis generation and target identification in early drug research to patient recruitment, comparative effectiveness evaluations, indication expansion, and post-marketing pharmacovigilance.

Steve Lethbridge, Senior Vice President of Global Partnerships at TriNetX, emphasized the significance of this achievement, stating, "The 300 million milestone is just that—a milestone, not an end goal. What a network of 300 million patients enables is far more important than the number itself. In all areas of healthcare where decisions affect patient outcomes, the difference between a sound decision and a mere guess hinges on the trustworthiness, timeliness, clinical relevance, and global representativeness of the data. That’s exactly what this network provides."

Notably, the strongest growth of the TriNetX network has been observed outside the United States. Among the nearly 52 million patients added from April 2025 to April 2026, the majority were from international markets. Currently, the network comprises 186 million patients in the U.S., 72 million in the EMEA region, 23 million in Latin America, and 21 million in APAC.

The international reach of TriNetX LIVE™ is not a coincidence; it is embedded in the functioning of the network itself. Unlike aggregated extracts reprocessed by a third party, the TriNetX LIVE™ network operates in a live, bidirectional manner. Data flows continuously from the electronic health record (EHR) systems of participating healthcare organizations, ensuring that updates occur almost in real-time while retaining complete clinical context.

Organizations interested in transforming real-world data into evidence for informed decisions can request a demo of the TriNetX LIVE™ network. This service has the potential to significantly enhance decision-making processes within organizations, promoting better patient outcomes.

About TriNetX


TriNetX is known as The Global Truth Engine for Better Human Health™, helping organizations understand what truly occurs in patient care. By connecting health systems, researchers, and companies worldwide with actionable real-world patient data, TriNetX enables more informed decision-making based on solid evidence rather than assumptions. The data is sourced directly from over 13,000 healthcare facilities across more than 20 countries, ensuring accuracy, privacy, and trustworthiness. TriNetX combines these data with expertise and technology to assist clients in asking better questions, interpreting outcomes, and moving forward with confidence.

For further details, visit www.trinetx.com or follow TriNetX on LinkedIn.

Media Contact:
Karen Tunks
Email: [email protected]
Logo: TriNetX Logo

Topics Health)

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