Acorai Enrolls First Patient in Groundbreaking HOSP-HF Study for Heart Failure Insights

Acorai Initiates the HOSP-HF Study

Acorai has reached a significant milestone by enrolling the first patient in its ambitious HOSP-HF study. This observational research will include 1,000 patients and aims to explore the association between non-invasive congestion assessments and health outcomes for patients hospitalized with heart failure. Conducted across multiple sites in Europe, Asia, and the United States, the study sets its course for the year 2026.

The Clinical Challenge

Heart failure remains a pressing concern within the healthcare landscape. One of the pivotal issues following hospitalization for heart failure patients is the presence of residual congestion at discharge. Such congestion is a known factor that leads to patient deterioration shortly after leaving the hospital, yet current discharge-readiness assessments often involve subjective evaluations and inconsistent methods that do not accurately reflect a patient's hemodynamic stability.

The HOSP-HF study is designed to gather objective data using Acorai's innovative, non-invasive sensing devices. Over the course of the patients' hospitalization, daily assessments will be recorded, culminating in a comprehensive analysis right before discharge. This observational approach will provide significant insights into how objective congestion evaluations can influence patient outcomes after a heart failure episode.

Objectives of the HOSP-HF Study

The core objective of the HOSP-HF study is to determine whether the application of Acorai's investigational device during hospitalization and near discharge correlates with improved outcomes 30 days post-discharge. This will include assessing standard care markers alongside the unique congestion assessments provided by the device.

Statements from Experts

Dr. Andrew J. Sauer, Co-Director of the Cardiovascular Research Clinical Scholars Program at Saint Luke's Mid-America Heart Institute, highlighted that the HOSP-HF study will stipulate a new standard in defining readiness for discharge.