Kōraku's NMN Innovation
2025-07-31 00:45:08

Innovative NMN Technology Development by Kōraku Co., Ltd. Gains Patent Approval

Kōraku Co., Ltd. Secures Patent for Innovative NMN Technology



Kōraku Biotechnology Co., Ltd., headquartered in Chiyoda, Tokyo, has received patent approval for its unique technology combining NMN (Nicotinamide Mononucleotide) and Lumbricus rubellus, a special type of earthworm powder. The patent, filed on June 9, 2025, (Patent Application No. 2025-095841), represents a significant advancement in health support.

The research and development of this innovative formula has been overseen by Dr. Athena Yang, who has an extensive background in biochemical studies from the University of Tokyo and aging research at the Massachusetts Institute of Technology (MIT). The combination of NMN, a vitamin B3 derivative, and Lumbricus rubellus is believed to enhance each component's natural benefits, promoting better health habits on a daily basis. This technology especially aims to support individuals concerned about their health and those sensitive to seasonal changes.

To bring this cutting-edge formula to market, Kōraku has launched a new supplement named '18' (KRK 18), available for purchase on Amazon. The company intends to continue exploring this technology to enhance the quality of life for its consumers by offering effective and reliable health supplements.

Understanding the Ingredients: NMN and Lumbricus Rubellus


What is NMN?


Nicotinamide Mononucleotide (NMN) is a natural substance present in the body that is derived from vitamin B3 (specifically Nicotinamide). This vital component is naturally found in food sources but has been known to diminish with age, leading to increased interest in its supplementation for health maintenance.

The Role of Lumbricus Rubellus


Lumbricus rubellus is a protein-rich, fermented ingredient gaining popularity among health-conscious consumers. It employs traditional knowledge in its applications and has been utilized in specific regions due to its health properties.

This new patented technology combines NMN and Lumbricus rubellus in specific ratios to maximize their respective benefits. Unlike traditional methods where these ingredients were consumed separately, Kōraku's tech optimizes the blend based on composition, stability, and processability, thus providing a new avenue for practical product development.

Research indicates potential benefits in areas such as:
  • - Balancing Lipids and Sugars: Focusing on maintaining a healthy metabolic balance.
  • - Supporting Circulatory Health: Aiming to promote overall circulatory systems.
  • - Addressing Stress Rhythms: Considering external and internal stress factors affecting the body.
  • - Enhancing Daily Performance: Technologies that assist in sustaining vitality and everyday performance.

A Commitment to Family Health


The inspiration for Kōraku's health care project stems from a universal desire to enhance family well-being. The company's founder maintained a strong desire for the health of loved ones, catalyzed by the recognition of health risks associated with traditional diets in colder regions, particularly in Northeast Japan.

With insights from Dr. Yang, the company began developing its supplement products with a focus on quality and reliability. The initial aim was to rectify the presence of low-quality or counterfeit products in the market by ensuring a trustworthy, high-purity offering.

As a result of continuous discussions and research, the development process led to the creation of '18,' which seeks to harmonize with the user’s daily health habits, receiving positive feedback from early users.

Product Design and Features


The design of the '18' supplement reflects Kōraku's intention behind the product: 'to promote the health of families.' Its sophisticated monochrome packaging design, featuring traditional Japanese patterns, symbolizes healthy growth and well-being. Manufactured in GMP-certified facilities in Japan, the product aims to ensure quality from the ground up.

Future Aspirations


Following this initial patent approval and product launch, Kōraku aims to gather clinical data both domestically and internationally, focusing on enhancing reliability through scientific research. The company is committed to fostering health outcomes not just locally but globally, with future plans to create a comprehensive health care platform centered around supplements to support people across all generations.

To achieve these ambitions, Kōraku plans to leverage advanced technologies, particularly AI, for its marketing strategies in expanding their reach in the booming e-commerce environment, ensuring that their health products reach those who need them most.

Company Overview


Kōraku Biotechnology Co., Ltd.
  • - Location: 5-2-2 Sotokanda, Chiyoda-ku, Tokyo, Japan
  • - CEO: Ryu History
  • - Founded: June 12, 2024
  • - Business: Development and sale of health supplements and other products.
  • - Website: Kōraku Co., Ltd.

Contact Information


Marketing Contact: Takahiro Abe / Email: [email protected]

Through its innovation in health technology, Kōraku Co., Ltd. is poised to contribute to better health for families worldwide, reflecting the vision of leading technology and creating a joyful future together.


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Topics Health)

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