Volta Labs and Watchmaker Genomics Launch Callisto™ Complete Kit for DNA Prep at AGBT 2026
Launch of the Callisto™ Complete Kit
At the Advances in Genome Biology and Technology (AGBT) 2026 General Meeting held in Orlando, Florida, Volta Labs, a pioneer in next-generation sequencing (NGS) automation, revealed its latest innovative product, the Callisto™ Complete Kit for DNA EF Library Prep. This cutting-edge kit combines superior sample preparation chemistry from Watchmaker Genomics with Volta’s advanced digital fluidics automation, offering a seamless, fully automated workflow for PCR-free whole genome sequencing (WGS) library preparation.
As demand for whole genome sequencing continues to surge in clinical and research settings, the need for efficient and reliable workflows grows. PCR-free methods are increasingly favored to avoid amplification bias, mitigate sequencing artifacts, and ensure even genome coverage, especially in GC-rich regions. Developing a successful PCR-free library preparation workflow necessitates precision and repeatability—traits that automation uniquely provides. By minimizing manual liquid handling and the variability it introduces, the Callisto™ Complete Kit empowers laboratories to produce high-quality, reliable libraries while allowing technicians to redirect their efforts to more complex tasks.
Udayan Umapathi, CEO of Volta Labs, emphasized the company's commitment to innovation in sequencing. “Callisto was designed with the intention of simplifying the sample preparation process while making it more accessible for laboratories. The complete kit allows for PCR-free workflows to run seamlessly at the push of a button, consistently delivering high-quality results suited for practical, mid-throughput applications.”
Complementing this, Trey Foskett, CEO of Watchmaker Genomics, highlighted the importance of both high-performance reagents and procedural precision. “For clinical and translational laboratories seeking reliable, push-button solutions without the need for extensive throughput, the Callisto™ Complete Kit paves a straightforward and efficient route to performing PCR-free WGS confidently.”
The official launch of the Callisto™ Complete Kit was celebrated with an informative presentation in a suite at the AGBT 2026 meeting. Scheduled for February 24 at 8:30 AM in the Fulton Suite, the session provided attendees with insights into the capabilities of the kit, a demonstration of the automated PCR-free WGS workflow, and opportunities to engage directly with the teams behind the innovation.
About Volta Labs
Volta Labs is on the forefront of transforming sequencing sample preparation by integrating digital fluidics, modular workflows, and complete walk-away automation within a single platform. The Callisto™ kit represents their vision of producing high-quality, reproducible NGS library preparation tailored for whole-genome, targeted, and custom applications. The headquarters of Volta Labs is in Boston, Massachusetts.
About Watchmaker Genomics
Watchmaker Genomics operates at the intersection of advanced life sciences, focusing on crafting high-performance tools that enhance genomic research and clinical applications. With expertise in protein engineering and NGS, the company provides accurate and efficient reagents alongside platforms that elevate molecular analysis to new standards. Watchmaker Genomics is dedicated to propelling breakthrough technologies that facilitate innovations in cancer detection, epigenetics, and liquid biopsy techniques.
This launch marks a significant step forward for laboratories looking to enhance their sequencing capabilities while ensuring reliability and precision through automation.